Best way to remember major functions of G protein linked receptors?

[purplelife]

What's the best way to remember the major functions of alpha, beta, muscarinic, dopamine, histamine, vasopressin? I always have hard time recalling which does what. I searched online and couldn't find anything useful..

So, does anyone have a better way to remember these than plain memorization?


Thanks

Edit: The top part on F.A-2012 pg 263, not the bottom part about Kiss, kick,...

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[bangarang]

What's the best way to remember the major functions of alpha, beta, muscarinic, dopamine, histamine, vasopressin? I always have hard time recalling which does what. I searched online and couldn't find anything useful..

So, does anyone have a better way to remember these than plain memorization?


Thanks

FA-2012, pg 263

FA2013 has great mnemonics for that, and it's the way I learned it.

Have one M&M = HAV1 M&M = H1, A1, V1, M1, M3 = Gq

MAD 2's = M2, A2, D2 = Gi

The rest = B1, B2, H2, V2, D1 = Gs. No mnemonic for this one, but I can think of something off the top of my head. Like... Be one Be Two, HaVe 2 make Division 1.

 

[Jamiu22]

FA2013 has great mnemonics for that, and it's the way I learned it.

Have one M&M = HAV1 M&M = H1, A1, V1, M1, M3 = Gq

MAD 2's = M2, A2, D2 = Gi

The rest = B1, B2, H2, V2, D1 = Gs. No mnemonic for this one, but I can think of something off the top of my head. Like... Be one Be Two, HaVe 2 make Division 1.

Kiss kick until ur sick of sex (Qiss qiq siq sqs)

a1 a2 b1 b2 m1 m2 m3 d1 d2 h1 h2 v1 v2

Write that down 5 times and you should have it down (2 days in a row)

 

[tiedyeddog]

You just gotta keep writing it. I have made flash cards and that has helped a ton.

Another thing, try to memorize what occurs in overdose and what the antidote is. That helps you to understand the physiology a bit better.

The MAD2's, HAVe1 m&M3, and qiq siq mnemonics also help. just keep writing them out, it'll eventually stick.

 

[Jonari]

You just gotta keep writing it. I have made flash cards and that has helped a ton.

Another thing, try to memorize what occurs in overdose and what the antidote is. That helps you to understand the physiology a bit better.

The MAD2's, HAVe1 m&M3, and qiq siq mnemonics also help. just keep writing them out, it'll eventually stick.

this.

had a teacher in med school that made us draw these pathways out repeatedly...always thought it was such a waste of time...granted, looking back at it now - i'm extremely grateful. i'd say signaling pathways is probably one area of questions, i always get right. only pathway im not really familiar with is the mTOR/Akt pathway.

 

[purplelife]

FA2013 has great mnemonics for that, and it's the way I learned it.

Have one M&M = HAV1 M&M = H1, A1, V1, M1, M3 = Gq

MAD 2's = M2, A2, D2 = Gi

The rest = B1, B2, H2, V2, D1 = Gs. No mnemonic for this one, but I can think of something off the top of my head. Like... Be one Be Two, HaVe 2 make Division 1.

Thanks for your response, but that's not the part I'm talking about. I'm talking about the part above, where they mention alpha one's major functions: increase vascular smooth muscle contraction, increase pupillary dilation, and so on.

 

[bangarang]

Thanks for your response, but that's not the part I'm talking about. I'm talking about the part above, where they mention alpha one's major functions: increase vascular smooth muscle contraction, increase pupillary dilation, and so on.

My mistake. No clue there.

 

[tiedyeddog]

Thanks for your response, but that's not the part I'm talking about. I'm talking about the part above, where they mention alpha one's major functions: increase vascular smooth muscle contraction, increase pupillary dilation, and so on.

Ok, here is another tidbit:

understand why reflex tachycardia and bardycardia occurs. Start to learn what drugs are given for what, and that well help you learn the mechanism:

example: Tamulsoin alpha-1 antagonist.
What is it used for? Symptomatic BPH, which means your prostate is so large the urethral lumen is compressed making it hard to pee. It helps you pee, so it must relax the bladder sphincter.

What does an a1 receptor do? it must contract the bladder.

example: albuterol. What was it do? b2 agonist.
What is it used for? used as a bronchodilator during acute asthma/COPD attacks.

what does a B2 receptor do? must bronchodilate. Also, what are the sideffects of a B2 agonist? fast heart rate and tremors. what else must they do? speed on heart rate and stimulate muscle excitation.

Atropine: what is it used for?
Bradycardia and also as an antidote to cholinesterase inhibitors + direct cholimemetics. If it speeds up the heart, muscarinics must slow it down.

on and on and on. You know what many of these drugs treat (what are B-blockers for?) now tie in the physiology.

 

[purplelife]

Ok, here is another tidbit:
.......

on and on and on. You know what many of these drugs treat (what are B-blockers for?) now tie in the physiology.

That makes sense. I will try that, thanks...

 

[stormchao]

this.

had a teacher in med school that made us draw these pathways out repeatedly...always thought it was such a waste of time...granted, looking back at it now - i'm extremely grateful. i'd say signaling pathways is probably one area of questions, i always get right. only pathway im not really familiar with is the mTOR/Akt pathway.

No one understands the mTOR pathway, it is just a jumble of weird letters. I think it is just a made up pathway meant to confuse medical students.

 

[Jonari]

No one understands the mTOR pathway, it is just a jumble of weird letters. I think it is just a made up pathway meant to confuse medical students.

how'd it go yesterday? why you up so early?