breast path q

[MudPhud20XX]

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A 45-year-old woman feels a “lump” in her left breast. Her physician palpates a 2-cm irregular area in the upper outer quadrant. A biopsy is performed and microscopic examination shows no evidence for carcinoma. Which of the following microscopic findings in this biopsy is most likely to suggest an increased risk for subsequent development of breast carcinoma?

A. Fat necrosis
B. Galactocele
C. Lobular epithelial hyperplasia
D. Multiple cysts
E. Sclerosing adenosis

 

[RLSGrasshopper]

Sclerosing Adenosis?

 

[NCmedstudent]

E.

but atypical something is the #1 increased risk. remember that from pathoma

 

[tropocollagen]

Sclerosing adenosis.

Epithelial hyperplasia with atypical cells will increase the risk. But 'lobular epithelial hyperplasia' means no atypical cells right?

 

[MudPhud20XX]

Sclerosing adenosis.

Epithelial hyperplasia with atypical cells will increase the risk. But 'lobular epithelial hyperplasia' means no atypical cells right?

That's a good point. The answer is C actually so looks like epithelial hyperplasia = atypical hyperplasia. Anyone has a better explanation?

 

[tropocollagen]

That's a good point. The answer is C actually so looks like epithelial hyperplasia = atypical hyperplasia. Anyone has a better explanation?

You're right. http://www.cancer.org/healthy/findc...s/non-cancerous-breast-conditions-hyperplasia

 

[Macaroon_Berry]

Remember this from pathoma - all hyperplasias increase the risk for cancer EXCEPT benign prostatic hyperplasia.

 

[MudPhud20XX]

Remember this from pathoma - all hyperplasias increase the risk for cancer EXCEPT benign prostatic hyperplasia.

Excellent point! Thanks!

 

[NCmedstudent]

Remember this from pathoma - all hyperplasias increase the risk for cancer EXCEPT benign prostatic hyperplasia.

and hyperplastic polyps!