Step I Ca2+ channel blockers

[aspiringmd1015]

Advertisement - Members don't see this ad

Kaplan pharm mentioned they dont work on the ventricle muscle actoin potential, but UW just mentioned they do decrease contractility besides their av nodal delay they cause, however, if they do work on contractility, that would mean they work on the ventricular action potential(phase 2)? Can someone clear this concept up for me?

 

[seminoma]

They work on both. The primary effect is in the AV node.

 

[aspiringmd1015]

so they delay phase 0 for the nodal AP, and shorten the plateau for ventricular AP?