Step I Coombs test

[hamza4ever]

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🙂 would anyone b so kind as to explain the difference between Coombs test (direct/indirect) and the importance of it. i never seem to get that down in my head.😕

thanks,......take care and keep smiling.🙂

 

[mpp]

The direct Coomb's test looks for auto-antibodies to RBC's by checking for IgG bound to RBC's using anti-IgG antibodies. The direct Coomb's test is used to check for immune mediated hemolytic anemias.

The indirect Coomb's test detects allo-antibodies to a donor's RBC's in a patient's serum for Rh-system matching when transfusing blood.

 

[hamza4ever]

thanks for the reply. i appreciate it.
🙂 definitely feel better now.
take care and keep smiling....🙂 🙂