Overall, i would say NO. Go to whichever school you would rather go too. I graduated from a tough school (UCSD) and in retrospect i wish i would have gone to a slightly easier school because my gpa is a little low. Definitly if you graduated from Harvard, or Yale or some ivy league then it helps for sure. Otherwise its mostly a numbers game. Some adcoms take your school into consideration, but overall, its all about the gpa (and DAT scores.)