drug interference with DNA replication

[mcgill2012]

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if a drug interferes with replication, apparently the cell cycle would arrest in S phase..
i dont really understand this though --> wouldnt the cell actually arrest in G1, because a checkpoint would prevent it from entering S?

 

[lorenzomicron]

this depends on the specific mechanism of the drug

 

[super6]

DNA replication only occurs in the S "synthesis" Phase, as it preps for mitosis. In the other phases, (g1 and g2), the organelles are being synthesized using cell machinery