The most significant changes in DSM5 will be the dimensionalizing of the personality disorder chapters (of the least valid former disorders), and the fact that this will be DSM 5.0, not DSMV.
The latter point is that there will not be a twenty year gap between a DSMV and a DSMVI, but rather there will be the ability for iterative changes based on new developments, especially with regards to neuroscience and biomarkers.
There will be some other things, some shuffling of the number of criteria for things here, the renaming of autism and mental ******ation, the dissolution of substance abuse and dependence, possibly some risk-syndromes. But these are mild updates that will not require drastic paradigm shifts to understand.