European Anxiolytics

[magni323]

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Why are there some therapies that are unheard of the USA but, are efficacious and utilized in other countries? I have noticed this especially among Anxiolytics. Seems most choices come down harder drugs i.e possible side effects and addictions like Benzos and SSRI'S. In other countries the drug is for the most part used for Anxiety and not an off-label use.

Etifoxine: Similar anxiolytic effects as benzodiazepine drugs but does not produce the same levels of sedation and ataxia. Further, etifoxine does not affect memory and vigilance, and doe ot induce rebound anxiety, drug dependence, or withdrawal symptoms

Fabomotizole, Mebicar , among a few others.

 

[clausewitz2]

Why are there some therapies that are unheard of the USA but, are efficacious and utilized in other countries?

Because no company has thought it was worth submitting a new drug application to the FDA and pay the many millions of dollars for extensive clinical trials to get it approved.

Etifoxine: Similar anxiolytic effects as benzodiazepine drugs but does not produce the same levels of sedation and ataxia. Further, etifoxine does not affect memory and vigilance, and doe ot induce rebound anxiety, drug dependence, or withdrawal symptoms

Interesting to me that the EMA hasn't approved this either, seems to be pretty much a French thing. It doesn't seem to be regulated in the states one way or another so you can just buy it from a reputable nootropic vendor and have folks try it themselves. .

Fabomotizole, Mebicar , among a few others.

Yeaaaaah I've seen enough bad times with folks hooked on Phenibut and Selank to make me very wary of Russian super-drugs that claim to be non-addictive anxiolytics.

 

[birchswing]

I remember reading Lyrica was a first line anti-anxiety med in Europe. I feel like I've started seeing it used in the US for that more.