not a deciding factor, but those grades will be used as factors too.. if you haven't received an acceptance/interview yet, then i would stay away from anything below a B (not saying that if you get a C, you're done... but it would help you not to have any)
Could be a deciding factor if you have a low GPA because of bad early semesters. They might want to be able to see you can sustain multiple semesters with high GPA. So if you have an upward trending GPA it might be beneficial if you made a 4.0 or something.