It all depends on how competetive you are.... I applied to 28 programs got 24 interview offers and went on 13.... overkill on my part. A classmate of mine with weaker stats applied to 50+ programs got about 6 interviews and matched. It doesn't hurt to over-apply, and is better than reapplying in my opinion. Realize that you need approximately 6-8 interviews to guarantee a match and interview dates may conflict with each other requiring you to make a choice on which one to go to. Most people match with either their first or second choice, and almost no one ranks lower than sixth on their rank order list. As far as the match rank it is explained on the natmatch site... but briefly if you rank Florida #1 and they rank you #20 but they don't get their 2 matches in the 1st 19 ranks, the spot is yours. If you ranked Jacksonville #2 and they ranked you #1 you still get Florida as your match. It is weighted in the candidates favor, and not a cumulative rank score or program preference. Rank according to your preference, not according to how you think the program will rank you and don't worry about it. I did not think I had a snowballs chance in hell matching at my top choice since I didn't extern there, but I thats where I am... I know of an individual who ranked their first choice a program they were sure they would match at... The person thought they wouldn't match at a better program and wanted to be able to say they got their top choice. It turned out that a program they wanted to go to more didn't match a spot and had ranked them, although low on their list. Rumor through the grapevine is that they regret it...