Glycolyltic Pathway -- Need to know?

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Divineimpetus said:
I am looking at kaplan's diagram of the glycolytic pathway and praying that we don't have to know all 9 steps of glycolysis.

How much information do we have to know about photosynthesis and respiration?

haha. I'm not laughing at you, I just went over that chapter ( 8 I think?) too, and I'm hoping the same thing.
 
Divineimpetus said:
I am looking at kaplan's diagram of the glycolytic pathway and praying that we don't have to know all 9 steps of glycolysis.

How much information do we have to know about photosynthesis and respiration?


I had two questions on my test about it. The first was what glucose is first converted to in the glycolytic pathway, which is glucose 6-phosphate. I also had a question which asked for the first irreversible step in the glycolysis, which is going from fructose 6-phosphate to fructose 1,6-bisphosphate. All this info was in the Kaplan AP bio review book I used. Hope this helps.
 
Divineimpetus said:
I am looking at kaplan's diagram of the glycolytic pathway and praying that we don't have to know all 9 steps of glycolysis.

How much information do we have to know about photosynthesis and respiration?

If you've taken biochemistry, then you allready know EVERY step, from back to front, including all of the enzymes that catalyze each step in the metabolic pathway. You know the above not only for glycolysis, but also the krebs cycle and the electron transport chain. Make sure you know 3 point fit in terms of specificity :scared: .

If you did not take biochemistry, good luck :luck:



:laugh: I'm joking (of course),

I think as long as you understand the 'overall picture', you should be fine. Dont need to really remember specifics. However, the irreversable reaction mentioned earlier in this thread by cowsgomoo is important, now here's my question:

Why is it important for the reaction to be irreversible in terms of the utility of glycolysis?

Knowing these kinds of things (conepts) will help you remember 😉 .
 
I had two questions on my test about it. The first was what glucose is first converted to in the glycolytic pathway, which is glucose 6-phosphate. I also had a question which asked for the first irreversible step in the glycolysis, which is going from fructose 6-phosphate to fructose 1,6-bisphosphate. All this info was in the Kaplan AP bio review book I used. Hope this helps.

Thanks Cowsgomoo. That's something I never learned in my first two semesters of biology. It seems like the DAT goes far more in depth than what most students think it does.
 
Divineimpetus said:
I am looking at kaplan's diagram of the glycolytic pathway and praying that we don't have to know all 9 steps of glycolysis.

How much information do we have to know about photosynthesis and respiration?

hey dont forget the steps on photosynthesis, i got caught up there 😡 😱
 
Divineimpetus said:
I am looking at kaplan's diagram of the glycolytic pathway and praying that we don't have to know all 9 steps of glycolysis.

How much information do we have to know about photosynthesis and respiration?


you do not have to memorize all of the steps in glycolysis...know the end products/intermediate products of glycolysis, pyruvate decarb., krebs, etc. I did not have any questions regarded individual steps b.c. that would be in depth biochem, and they do not expect us to know all of that. I still managed a 23 in bio and did not fool with biochem when studying. Good luck.
 
Divineimpetus said:
I am looking at kaplan's diagram of the glycolytic pathway and praying that we don't have to know all 9 steps of glycolysis.

How much information do we have to know about photosynthesis and respiration?
YES! Know the glycolytic pathway inside and out! My first question was on the pathway and its products. YOu may get a different test than me, but it doesnt hurt to know it as I am sure any other version of the DAT will test you on it somehow.
 
cowsgomoo said:
I had two questions on my test about it. The first was what glucose is first converted to in the glycolytic pathway, which is glucose 6-phosphate. I also had a question which asked for the first irreversible step in the glycolysis, which is going from fructose 6-phosphate to fructose 1,6-bisphosphate. All this info was in the Kaplan AP bio review book I used. Hope this helps.

I have so much respect for you. I could not find that answer anywhere in my kaplan book or my own textbook. It bothered me forever until I finally gave into google.

From what I have researched it turns out that any reaction that consumes or yeilds ATP is considered irreversible. Can anyone confirm or deny this?
 
Divineimpetus said:
I have so much respect for you. I could not find that answer anywhere in my kaplan book or my own textbook. It bothered me forever until I finally gave into google.

From what I have researched it turns out that any reaction that consumes or yeilds ATP is considered irreversible. Can anyone confirm or deny this?



from what i remember, reactions 1, 3, and the last one are irreversible. this is from my biochem class i took last semester. so the first irreversible step would be glucose to glucose 6 phosphate.
 
vikings022000 said:
from what i remember, reactions 1, 3, and the last one are irreversible. this is from my biochem class i took last semester. so the first irreversible step would be glucose to glucose 6 phosphate.


Thanks Viking. I am really regretting I did not take Biochem, Anatomy and Physiology now. That DAT seems to get a little bit more detailed than the basic introductory year of biology.
 
vikings022000 said:
from what i remember, reactions 1, 3, and the last one are irreversible. this is from my biochem class i took last semester. so the first irreversible step would be glucose to glucose 6 phosphate.

NOT true. F6P to F1,6bP is the 1st committed step. Once you pass this step you are committed to glycolysis.
 
dat_student said:
NOT true. F6P to F1,6bP is the 1st committed step. Once you pass this step you are committed to glycolysis.

I believe F6P to F16BisP is the 1st committed step not glucose to G6P because this step only keeps the glucose inside the cell. G6P doesn't necessary have to be used in glycolysis since it can be used in making glycogen in the liver. But, I think if the question is asking for the first irreversible step, it's the hexokinase step going from glucose to G6P since it utalizes an ATP molecule. Depends on how the question is asked.
 
Divineimpetus said:
I have so much respect for you. I could not find that answer anywhere in my kaplan book or my own textbook. It bothered me forever until I finally gave into google.

From what I have researched it turns out that any reaction that consumes or yeilds ATP is considered irreversible. Can anyone confirm or deny this?


Dude don't give me that much credit I only knew it because it was in my AP bio review book that I used. I am a chem major so my bio is not that hot and I was very surprised that I even remembered this fact on test day.
 
cowsgomoo said:
Dude don't give me that much credit I only knew it because it was in my AP bio review book that I used. I am a chem major so my bio is not that hot and I was very surprised that I even remembered this fact on test day.

Did they ask for the 1st committed step or the 1st irreversible step?
 
Correct me if I'm wrong, Pyruvate Kinase step is also irreversible since it has a large negative delta G. But, I'm pretty sure that the first irreversible step is the hexokinase step. 😎
 
miravyn said:
Correct me if I'm wrong, Pyruvate Kinase step is also irreversible since it has a large negative delta G. But, I'm pretty sure that the first irreversible step is the hexokinase step. 😎

isn't the large "negative" delta G an indication of spontaneity?!
 
dat_student said:
isn't the large "negative" delta G an indication of spontaneity?!

It just means that it is energically favorable to go in that direction. I suppose that since it's so favorable, it will most likely go in that direction, from PEP to pyruvate. Since it is so favorable in the direction of PEP to pyruvate, alterative enzymes (PEPCK and something else) are required to drive the reverse reaction from pyruvate to PEP in gluconeogenesis.
 
miravyn said:
It just means that it is energically favorable to go in that direction. I suppose that since it's so favorable, it will most likely go in that direction, from PEP to pyruvate. Since it is so favorable in the direction of PEP to pyruvate, alterative enzymes (PEPCK and something else) are required to drive the reverse reaction from pyruvate to PEP in gluconeogenesis.

energetically favorable = spontaneous, same thing...spontan. & rxn rate 2 diff things.
 
Do we have to know photosynthesis? I think it's a bigger pain in the butt than cell respiration. I'm using Examkracker bio to study instead of Kaplan because it is colored. hehe. Anyway, it mentions nothing on photosynthesis.
 
miravyn said:
Do we have to know photosynthesis? I think it's a bigger pain in the butt than cell respiration. I'm using Examkracker bio to study instead of Kaplan because it is colored. hehe. Anyway, it mentions nothing on photosynthesis.

YES, we should...
 
miravyn said:
Do we have to know photosynthesis? I think it's a bigger pain in the butt than cell respiration. I'm using Examkracker bio to study instead of Kaplan because it is colored. hehe. Anyway, it mentions nothing on photosynthesis.
EK is for the MCAT. It teaches physiology well, but doesnt talk about anything else.
 
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