Gower's sign

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EM2BE

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I was wondering what all the possible diagnoses could be for someone with a positive Gower's sign. We recently learned it is one of the diagnostic indicators for some of the muscular dystrophy disorders. Anyone here know of any other possibilities (besides generalized muscle weakness)? The reason I ask is because I was trying to figure out if this would be a prime indicator for just these disorders or if it is used for other disorders too.

Thanks.
 
To my knowledge (albeit limited) Gower's sign is pathognomonic for MD, and is not prominently displayed in other muscular disorders. If I remember, this plus calf pseudohypertrophy are basically diagnostic...
 
Gowers sign can be seen with several types of proximal muscle weakness, including the dystrophinopathies (Duchenne, Becker), congenital myopathies (central cores, nemaline rod), limb girdle myopathies. It can also be seen with back pain and juvenile idiopathic arthritis
 
Gowers sign can be seen with several types of proximal muscle weakness, including the dystrophinopathies (Duchenne, Becker), congenital myopathies (central cores, nemaline rod), limb girdle myopathies. It can also be seen with back pain and juvenile idiopathic arthritis

Who let this guy in?

YOU, out of here!

[/joking]
 
Thanks all of you!!
 
Sorry, but I was attracted by the EEG in HIANMI'S avatar. It's kinda like opossums and headlights.

😕 Don't think I've seen that one yet...
 
Gowers sign can be seen with several types of proximal muscle weakness, including the dystrophinopathies (Duchenne, Becker), congenital myopathies (central cores, nemaline rod), limb girdle myopathies. It can also be seen with back pain and juvenile idiopathic arthritis

yeah, what he said.

on a related note-- i recently worked up a pt referred to us for short stature and isolated elevated AST/ALT. otherwise completely normal 2yo with normal routine short stature labs . . except for a CK my attending wanted to order that was in the 40,000 range and an elevated LDH. most likely duchenne's. sad 🙁 on a further review, the only possible other clue to this was he walked at 16 months.

--your friendly neighborhood heartbroken caveman
 
How often does Gower's show positive for the first time in adulthood?
 
i dunno. i take care of kids. but the mechanism behind the maneuver (weakness) would lead down a path of neurological or muscle dysfunction (either via glycogen or structural protein issues).

--your friendly neighborhood gower power caveman
 
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