Great questions to try! HY

[Canadianey]

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Here are some good practice questions that you guys can try.
I wrote them myself from numerous sources.
Just some things I think are very high yield and might help.

1. Pt is from Egypt and now presents with painless hematuria ... His condition could have been prevented by admin of which drug?
2. Patient presents with an infection after placement of a shunt. The organism shows extra cellular matrix formation. What is the drug of choice?
3. HIV patient presents with seizures. MRI shows ring enhancing lesion. What is the drugs mechanism of action?
4. Patient has severe asthma, presents to the emergency. Pt is sent home after a drug is given. One week later, the patient comes for a follow up and you see a layer of white exudate on the tongue. What drug can you give to treat this condition? What is the mechanism of action?
5. Patient has a fungal infection in the toe nail, and a drug is prescribed. What is the mechanism of action?
6. Patient comes back from a trip that he took in Africa. He comes to the doctor complaining of fevers that occur at 48 hour spikes. What is the drug of choice for this condition?
7. Patient comes in with a high fever and non productive cough. Examination shows pneumonia. There is cold agglutination. How does this drug develop resistance?
8. Patient presents to you with a creamy discharge after having sexual intercourse with 3 people in Aruba last week. What is the drug of choice for this condition?
9. Patient comes to you with inappropriate laughter, puppet like movements. Karotype is normal. You conclude that the patient is suffering from an imprinting disease. Which pathway has a def?
10. Pt delivers child, prematurely, now comes with tender uterus and foul smelling discharge. What is the organism?
11. Patient has numerous proteus infections in the past, presents with upper urinary track infection. Lipid laden macs are seen in the mass. What is the condition?
12. Pt has a car accident, and has lost a lot of blood. What do you expect to see in regards to secondary messenger?
13. Pt has frontal baldness cataracts, and testicular atrophy. What is the mutation and the disease?
14. Pt has bilateral renal cell cancer and a liver cyst. What other characteristic is a feature of this disease?
15. Pt has elfin face, and is extremely friendly with strangers. He has well developed verbal skills. Pt also presents with hyperCa+. What is the mechanism behind the hyper Ca+?
16. Pt is born and has small head, with small feet. Severe cleft lip and palate is seen. Polydactyly is seen. What is another GI presentation of this patient?
17. Pt comes in with large jaw, large eyes and testes. Presents with severe mental ******ation. What is the location of the mutation?
18. Stimulation of a factor leads to severe bronchoconstriction, vasoconstriction and platelet aggregation. What is the secondary messenger involved?
19. Pt has a black liver. Biopsy shows metabolites of epinephrine. What is the mechanism by which the elevated bilirubin is transferred?
20. Which drug induces mania in bipolar patients?
21. Pt is bipolar. You give a drug. 3 months later is pregnant. What is the fetus at risk of developing? What is the pathogenesis of the disease?
22. Pt’s bone marrow test is TRAP positive. Which drug is resistant to adenosine deaminase?
23. Pt receives drug for seizures, and has high levels of Phenobarbital. What drug has caused this?
24. There are high levels of lactose, and increase levels of glucose. What happens to lac operon?
25. Pt has been fasting for the last 18 hours while on a hiking trip. He ends up having hypoglycaemia, hypoketones, increased glucagon and NH4+ levels. What is def? What pathway? What enzyme?
26. Child has trouble staying awake during the week. Falls asleep at 4 am in the morning, and unable to stay awake. During the weekends patient is okay, and seems to be doing well. What is the possible disease?
27. Patient has s100 positive. What is the mutation of the disease if it metastasizes? What is the treatment for the mets? MOA?