Hormones Made/Controlled by Hypothalamus

[justadream]

Are the hormones associated with the anterior pituitary the only hormones produced and "controlled" (via tropic hormones) by the hypothalamus?

I've read TPR and EK and it isn't very clear.

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[Mantis Toboggin]

So we know the mnemonic FLAT PEG refers to the hormones made by the anterior pituitary in response to the corresponding seven hypothalmic hormones

Other than that the only two I can remember that we need to know for the MCAT are oxytocin and adh. Both of these hormones are made in the hypothalamus but stored in the posterior pituitary.


Also what do you mean by "controlled?" Are you referring to the negative feedback systems when hypothalmic/ap hormone/tropic hormones are too high?

 

[justadream]

@Mantis Toboggin

I wasn't sure if posterior pituitary hormones were made/controlled by the hypothalamus.

By "controlled", I mean like by the hypothalamus using hormones to influence the pituitary. For example, the hypothalamus uses CRH (I think) to stimulate the AP to release ACTH. Is there an analogous "CRH" for each of the pituitary hormones?

 

[Mantis Toboggin]

Yes, absolutely. I don't know if they will be tested but better to be safe than sorry.

For the mnemonic FLAT PEG (FSH, lh, ACTH, tsh, prolactin, endorphins, and growth hormone)

FSH and lh by gonadotropin releasing hormone.

Tsh by thyroid releasing hormone (trh)

*****Prolactin by prolactin inhibitory factor(PIF aka dopamine). This one is likely to be tested because unlike the others, the ABSENCE of PIF causes prolactin to be released. Just remember by the name, it INHIBITS prolactin.

Endorphins-- not sure, let me know if you find this out, wasn't listed in my book

Growth hormones by growth hormone-releasing hormone

 

[IslandStyle808]

Actually the book that explains this pretty well is Kaplan Bio.

Hypothalamus releases------------------------------- Anterior Pituitary Releases from stimulation of Hypothalamus:
Gonadotropin-releasing hormone (GnRH) -------> FSH & LH
Growth hormone releasing hormone (GHRH) ---> GH
Prolactin inhibitory factor (PIF) -------------------> Prolactin
Thyroid-releasing hormone (TRH) ----------------> TSH
Corticotropin releasing factor (CRP) --------------> ACTH

All given in bold in the book. Also I remember a passage about one of the indirect hormones in the AAMC practice passages. So it is definitely possible you could be asked about one.

 

[sillyjoe]

This is a great schematic. Just note adenohypophysis is the anterior pituitary and the neurohypophysis is the posterior pituitary:

Also, I suggest for a better grasp on the subject you look up the difference between tropic and trophic

 

[justadream]

So the hypothalamus regulates the anterior pituitary via the Hypothalamic-Hypophysical Portal System.

As fro the posterior pituitary hormones, does the hypothalamus just directly innervate them (via axons)?

 

[Shirafune]

Right. The hypothalamus sends releasing/inhibiting hormones to the AP through a portal system, which then releases its own tropic hormones. The hypothalamus also contains nerve cells that innervate the PP. The hypothalamus controls the release of PP hormones through this way.