How much of DNA do i need to know for Step 1?

[mubacalypse]

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For anyone....

Dne structure, replication, transcription, epigenetics.....how much should i focus on these for Step 1? Thanks

 

[Lizloveslilies]

It really helps to have a firm grasp of DNA structure, replication, transcription, and epigenetics. Especially because a good bit of the questions on these subjects are experiment-based, explaining the mechanism of some aspect of cell-damage, or in conjunction with those high yield genetic abnormalities that show up on Step 1.

I think what is in the biochemistry (molecular) section of FA is good. Also it would help to look over purine/pyrimidine synthesis, and how DNA is assembled.

I would recommend also keeping genetics (inheritance modes, testing for certain medical conditions, etc.) in mind when studying this topic.

 

[speedyk]

I had at least 7 molecular/dna questions... 2 regarding the lac operon.

 

[Elbowstoopointy]

I had at least 7 molecular/dna questions... 2 regarding the lac operon.

Lac Operon on step 1? Is this real life?

 

[speedyk]

Lac Operon on step 1? Is this real life?

Yes. you could have figured 1 of them out based on the Question stem though (I think/hope). The other, no.

 

[Alvarez13]

I had at least 7 molecular/dna questions... 2 regarding the lac operon.

Noooooooooooo!

 

[WhyOhWhy]

I'm pretty sure you should memorize the first 8087657922111109 base sequences of chromosome 3. Ive heard it's super high yield.

 

[septoplasty]

I'm pretty sure you should memorize the first 8087657922111109 base sequences of chromosome 3. Ive heard it's super high yield.

I hate VHL.

 

[ArcGurren]

For serious - I would at least know the 3 kinds of stop codons: UAA, UGA, UAG. As well as the start codon (AUG). Reason being is that they could show you a sequence of DNA and ask you to identify the kind of mutation

 

[combat]

For anyone....

Dne structure, replication, transcription, epigenetics.....how much should i focus on these for Step 1? Thanks

I only had one DNA questions, which was so poorly drawn in step exam. But it was undergrad level question but again every exam differs.