Hsil??

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Marianne11

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I cannot find the answer to this, can anyone help? Does a pap that shows a HSIL mean it is cancer, or could be? What is the % of "is cancer" vs. precancer, infection, etc.? Thanks!
 
HSIL does NOT mean cancer, it means exactly what it says. High grade squamous intraepi lesion.

I dont know what hte percentages are.
 
There are many different cytology nomenclatures. The newer system the Bethesda system which starts as benign, atypical,LGSIL (low grade squamous), HGSIL, and CIS (carcinoma in situ pre cancer), Carcinoma (this then is cancer and staged according to extent of spread. HGSIL is eqivalent to CIN 2/3 in which 15% of CIN3 paps will progress to invasive cancer if untreated according to Desaia Clinical Gynecological Oncology 6th edition.

You probably do not have cancer. BUT>>>> A HGSIL pap needs special attention and most people will do a biopsy at the least by an exam called a colposcopy. This exam is basically like a pap smear but vinegar is applied to the cervix ((atypical cells will turn white and you may see punctated lesions, and abnormal vessels (the most worrisome sign for cancer)), then it is viewed with a low power microscope any suspicious areas are biopsied.

Remember the pap is ONLY a scrrening tool it is not a diagnosis. My guess is that you will need a colposcopy and a biopsy to say what abnormalities are present. The goal of is to rule out invasive cancer.

Now some OB/Gyn's with paps showing grades HGSIL, will automatically perform a LEEP or conization both are risky for cervical complications (usuallyb less than 10% of the time) in pregnancy (they can cause cervical stenosis and cause infertility or worse cause repetitive second trimester miscarriages from premature cervical dilation). However, a biopsy must be taken to rule out cervical cancer or if there are any glandular abnormalities which confers a worse prognosis. Remember it is a preventable disease and a pap can not make the diagnosis with certainty. Good luck feel free to private message me with outcomes or further questions.

Diane
 
Diane,

Thank you so much for your reply. I feel better now. I'm having the colposcopy tomorrow. I hope this ordeal is over soon and doesn't affect my interview/admission's process.

Thank you!!! 🙂
 
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