Hypofractionation for male breast ca?

[Mandelin Rain]

Have a guy with gynecomastia and a T1b breast ca s/p a central partial mastectomy. Not really a common issue. Anyone hypofractionate for male breast ca?

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[medgator]

"Males weren't included in the trials" so no. I kid. I don't see a problem if it's a lumpectomy and you aren't treating nodes

Any reason he didn't get a standard mastectomy? I haven't seen a lot of male breast ca but I thought that was pretty much the standard surgery

 

[Mandelin Rain]

Any reason he didn't get a standard mastectomy? I haven't seen a lot of male breast ca but I thought that was pretty much the standard surgery

Me too. Not sure why. I kind of shook my head at the whole thing.

 

[evilbooyaa]

Agree that mastectomy is generally standard of care.

Quick pubmed search shows one SEER database study that looked at it; seemed like lumpectomy was more in patients who had major medical co-morbidities, didn't get SLNB, were more likely not to get RT and had stage IV disease. Outcomes seemed a bit worse but apparently not SS, although they were looking at cause-specific survival.

https://www.ncbi.nlm.nih.gov/pubmed/23460016

In regards to the question, depends on if you're a study purist or OK with expanding indications. Don't see anything wrong with hypofrac if you can meet other reqs, but he'd probably get standard course at my institution.

 

[Palex80]

Go ahead and do partial breast irradiation!





Just kidding...