I have 2 important questions in regards to an assignment (which are not only for an assignment, but questions I came up with on my own that I personally want to know) which is:
1.) Is it proven that the constant excess release of glucocorticoids and glutamate from depression overstimulates neurons to exhaustion and causes the dendrites of neurons to retract, fail and wither away?
2.) If depression does, in fact, do this to the dendrites and exhausts the neurons, is it proven that there are temporary brief moments of greater depression that occur from this? Or are feelings of greater depression that result from this not instantaneous and takes time for a vast number of the dendrites to retract/atrophy and a vast number of neurons to exhaust in order for a feeling of greater depression to result from this? I know that there are obviously many instantaneous temporary brief moments of greater depression that can occur for someone who has depression, but again, are these moments of greater depression due to the retraction/atrophy of the dendrites and exhaustion of the neurons or due to something else?
Now are there arguments against the excess release of glucocorticoids and glutamate from depression causing retraction/atrophy of the dendrites and exhausting the neurons as well as arguments against instantaneous temporary brief moments of greater depression resulting from this? If so, feel free to post these arguments.
1.) Is it proven that the constant excess release of glucocorticoids and glutamate from depression overstimulates neurons to exhaustion and causes the dendrites of neurons to retract, fail and wither away?
2.) If depression does, in fact, do this to the dendrites and exhausts the neurons, is it proven that there are temporary brief moments of greater depression that occur from this? Or are feelings of greater depression that result from this not instantaneous and takes time for a vast number of the dendrites to retract/atrophy and a vast number of neurons to exhaust in order for a feeling of greater depression to result from this? I know that there are obviously many instantaneous temporary brief moments of greater depression that can occur for someone who has depression, but again, are these moments of greater depression due to the retraction/atrophy of the dendrites and exhaustion of the neurons or due to something else?
Now are there arguments against the excess release of glucocorticoids and glutamate from depression causing retraction/atrophy of the dendrites and exhausting the neurons as well as arguments against instantaneous temporary brief moments of greater depression resulting from this? If so, feel free to post these arguments.
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