In protein synthesis, how do tRNA and it's corresponding amino acid bind, forming aminoacyl-tRNA? Do

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m25

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in protein synthesis, how do tRNA and it's corresponding amino acid bind, forming aminoacyl-tRNA? Does it use anticodon binding at all?

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The anticodon does nothing. Each aminoacyl-tRNA has its own enzyme. So the tRNA and AA meet @ the active site of the given enzyme, ATP gets hydrolyzed, and BAM, you have your aminoacyl-tRNA complex.

What's key is that you have an enzyme for each AA. TRNAs with different anticodons use the same enzyme.
 
The anticodon does nothing. Each aminoacyl-tRNA has its own enzyme. So the tRNA and AA meet @ the active site of the given enzyme, ATP gets hydrolyzed, and BAM, you have your aminoacyl-tRNA complex.

What's key is that you have an enzyme for each AA. TRNAs with different anticodons use the same enzyme.
So you are saying that there's specific aminoacyl tRNA synthetase for each AA?
But I also heard that tRNA molecules have CCA 3' ends which covalently binds to an aa. Does this involve complementary base pairing?
 
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