Insulin Pathway to BloodStream?

[Dencology]

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Insulin secreted by Beta cells of pancreas, how does insulin enters bloodstream? (what is the pathway)

It has something to do with cascade effect. Insulin is a protein so it will bind to the cell membrane and cause a cascade CAMP effect. (only steroids go through cell membrane) Now, does this have to do any thing iwht RER and SER and Golgi app?

 

[Sea of ASH]

the pancreas is the only organ that is both an endo and exocrine system. so it secreates it into the blood.

now the signal is a different story. once in the bloodstream the target cells have surface proteins that recognize and bind insulin (protein hormone) and from there the cascade effect occurs