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Step I Intestinal Osteodysthrophy
Started by eduro25
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The small intestines are involved in Ca2+ absorption under the influence of PTH and vitamin D. If absorption is impaired involving deficits in any point of the system (more specifically, with respect to impaired or decreased action of 1,25 OH vitamin D on the intestine), osteodystrophy (impaired bone formation) occurs.
I guess it's because he posted 3 comments within 10 mins that had no contribution to any thread.
SomeDoc: Intestinal osteodystrophy is synonymous with renal osteodystrophy then?
analagous, yes, synonymous, no.
I think this condition develops when ca doesn't get absorbed through intestine(maybe lack of vit d or some intestinal infection or disease) body faces ca crisis,and low serum ca which may trigger PTH and ca starts breaking down from bones(because whatsoever serum calcium level to be maintained is what body system destined for).similar like chronic renal failure we see.just the cause here is intentinal malabsorbtion of Ca.
As a side note- diseases that cause malabsorption, particularly Crohn's or Ileal resection result in steatorrhea. Apparently free fats bind calcium --> decreased calcium absorption --> increased oxalate concentration in body (they bind calcium) --> Oxalate stones. Just a random aside.
