Iodide

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sc2016

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These two paragraphs are confusing to me. Isn't iodide used in hypothyroidism not hyperthyroidism?

Pharmacologic doses of potassium iodide are used to treat hyperthyroidism. They Inhibit the synthesis of thyroid hormone and the release of preformed thyroid hormone. Iodide is administered orally, and adverse effects include sore mouth and throat, rashes, ulcerations of mucous membranes, and a metallic taste In the mouth.

Iodine is involved in thyroid hormone biosynthesis, and iodine deficiency can cause goiter. Supplemental iodine is used to increase thyroid hormone production in parts of the world where iodine deficiency is endemic. Iodine deficiency should be suspected in patients with goiter and symptoms of hypothyroidism (constipation, weight gain, fatigue, and cold intolerance) who live in iodine-deficient areas. Radioactive iodine is, indeed, used as part of definitive therapy for hyperthyroidism and certain thyroid malignancies, but this is not the same as supplemental iodine.

 
These two paragraphs are confusing to me. Isn't iodide used in hypothyroidism not hyperthyroidism?

Pharmacologic doses of potassium iodide are used to treat hyperthyroidism. They Inhibit the synthesis of thyroid hormone and the release of preformed thyroid hormone. Iodide is administered orally, and adverse effects include sore mouth and throat, rashes, ulcerations of mucous membranes, and a metallic taste In the mouth.

Iodine is involved in thyroid hormone biosynthesis, and iodine deficiency can cause goiter. Supplemental iodine is used to increase thyroid hormone production in parts of the world where iodine deficiency is endemic. Iodine deficiency should be suspected in patients with goiter and symptoms of hypothyroidism (constipation, weight gain, fatigue, and cold intolerance) who live in iodine-deficient areas. Radioactive iodine is, indeed, used as part of definitive therapy for hyperthyroidism and certain thyroid malignancies, but this is not the same as supplemental iodine.

Potassium iodide is given to invoke the Wolf-Chaikoff effect, which is when the thyroid makes less thyroid hormone due to a downregulation of thyroid peroxidase.
 
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