Oops, I didn't mean to say that preclinical grades matter - they don't. All that matters from that era is your Step I score, which many programs use as a screening tool. Although they might waive that screening tool if you have a PhD. I still think your clinical grades, especially in the clerkship/field you want to go into, are huge. Let's face it, EVERY MSTP'er will match in their chosen field, what I was trying to get at (and didn't do so well) is that it's a question of where on your rank list that happens. If you are doing rad onc where everyone has a PhD or serious research experience, the # of slots is small, and the competition is fierce with a huge % of AOA, lame things like your clinical grades can potentially have a huge effect on where you match. Even in IM, I know people that weren't granted interviews at the top tier places (Hopkins, UCSF, BWH) despite having great PhDs and great test scores...maybe it was b/c they just High Passed IM? Who knows? Admittedly, the non-top tier places (i.e. most of the other top 20 IM programs) will almost embarrass themselves the way they throw themselves at MSTPers and basically beg them to come to their residency program and stay through fellowship to become junior faculty. I'm just saying if you want to shoot the moon, you gotta gun in 3rd year as unfortunate and loathsome as that might be.