LEUCOCYTE ADHESION DEFICIENCY

[sathyasai baba]

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CLINICAL FEATURES :
DELAYED SEPARATION OF UMBLICAL CORD

SO PATHOMA EXPLAINS: THAT AS SOON AS THE CHILD IS BORN THE UMBLICAL CORD WHICH HAD NORMALLY BLOOD FLOWING THROUGH IT IS SEALED CLAMPED AND DIES. THERES NO MORE BLOOD FEEDING IT AND THE TISSUE DIES OF NECROSIS.
AFTER NECROSIS COMES IN ACUTE INFLAMMATION .THIS ACUTE INFLAMMATION HELPS THE UMBLICAL CORD TO FALL OF FROM THE BABY.THIS IS BECAUSE THE NEUTROPHILS DESTROY THE TISSUE & THE CORD FALLS OFF.
BCOS OF LACK OF INTEGRINS THERE IS DELAYED SEPARATION.
from where do these neutrophils come when there is no blood flowing to the umblicus?

 

[Robotic Dock]

Base of the cord still connected to internal iliac artery and therefore PMN comes there and acts via integrins.

 

[Transposony]

Is something wrong with your cap lock?

 

[sathyasai baba]

Base of the cord still connected to internal iliac artery and therefore PMN comes there and acts via integrins.

thank you sir. sorry about the caps.