So at our school, we generally do 3 years of med school first before going to lab. So, we had been through the coursework years, cramming for step 1, all of those required rotations and rounds and call, and step 2. Then, they went on to MS4 rotations and we went to lab, where all of a sudden, none of that clinical knowledge helped me and I was a ******* all over again.
But, that year, we continued hanging out. Match day was hard (believe me...our program even has a yearly "Un-Match" party just for us MD/PhD students to commiserate!), but that stinging feeling of being left behind faded. They graduated, started intern year, generally hating it, just as I was getting into my lab groove. So, things got better.
Now, I'm about to go back to MS4. My close friends from my med school class are still my buddies-- they're all over the country but we keep in touch (the inappropriate text messages have not ended!). Basically, yes, there's a few months when it really sucks that you're still the n00b in lab while your friends are becoming actual doctors..but in the end, your close friends will stay your close friends no matter how behind you are 🙂