Mechanism of fatty change in reversible cell injury

[ChessMaster3000]

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I know that fatty change is listed as a reversible cell change in hypoxic injury. I was wondering what the mechanism of this was (couldnt find anything online). does anyone know?

 

[Fatalis]

one mechanism that comes to mind would be this
decr in 02 would lead to a decr in ATP=> less energy to run the Na-K pump which would lead to cell swelling and also ribosome splitting from RER; less proteins synthesized [lipoproteins for instance in the liver], therefore a decrease in fat transport.

 

[alicealicealice]

At least in the liver, hypoxia can also induce reductive stress (http://www.ncbi.nlm.nih.gov/pubmed/7488648) leading to a high NADH/NAD+ ratio.
Once you've got that you can imagine the same pathway that is seen in alcoholic fatty change: High NADH drives DHAP to Glycerol 3 P while simultaneously slowing beta oxidation of FFA. Fatty acids + glycerol --> lipid.
Just a guess though...