I took a W in a botany course taught by a male-hating lesbian who wore a different color sweater-vest everyday. I had a 3.5 and 20AA 20PAT when I applied, was accepted to four schools out of seven interviews. I think if they're early on in your academic career and not in O-chem or physiology or the likes, you'll be fine with a decent DAT score. If by multiple, you mean like more than 3 or 4, you may or may not have shot yourself in the foot on that one.