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- Sep 17, 2005
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1) Rapid efflux of newly secreted bile from canaliculi into the hepatic interstitium can be caused by structural disruption or functional alteration of which component of normal interaction between hepatocytes:
a) Adherens junction
b) Desmosome
c) Gap junction
d) Hemidesmosome
e) Tight junction
I have no idea
2) A 27 y/o female alcoholic with major depression tells the physician she has been repeatedly physically and emotionally abused by her partner. Appropriate response is:
a) Battering only grows worse with time. For your safety and self esteem it is in your best interest to leave this relationship.
b) Do you feel safe to go home?
c) Is there any way you can keep from getting him so angry?
d) There may be a correlation between your alcohol and the abuse. If you take steps to curb your alcoholism the abuse may subside
e) Why do you think your partner abuses you
A????
3) A study is done to determine if raloxifene prevents fractures. Results
Raloxifene: 138/2557 vertebral fractures (5.4%)
Placebo: 260/2576 vertebral fractures (10.1%)
How many women need to be treated with raloxifene to prevent one vertebral fracture?
a) 100/5.4 = 18.5
b) 100/10.1 = 10
c) 100/(10.1 + 5.4) = 6.5
d) 100/(10.1 5.4) = 21
e) 100/(10.1 x 5.4) = 2
D????
4) What antidiabetic causes orthopnea, pulmonary and peripheral edema, and an S3 gallop:
a) Acarbose
b) Glyburide
c) Metformin
D) Repaglinide
E) Rosiglitazone
5) The largest proportional increase in LV afterload and myocardial oxygen consumption occurs following a 20% increase in:
A) Aortic pressure
B) Coronary blood flow
C) Heart rate
D) Right atrial pressure
E) Stroke volume
In terms of increasing afterload, wouldnt it be A? But Im also thinking for myocardial oxygen consumption it would be C???
6) What causes brown kidney stones? There was nothing in the history, and the choices included hypercalcemia, hyperuricemia, and proteus infection (struvite). I looked these all up and couldnt find any particular color, so should I have gone with calcium since it is the most likely in terms of frequency?
7) A 30 y/o F undergoes thyroid resection because of CA. Within hours she develops neuromuscular excitability, severe cramping, laryngeal stridor, convulsions. TX is:
A) Intravenous bicarb
B) Vitamin A and K
C) Vitamin B6 (pyridoxine), B12, T3, and T4
D) Vitamin D and calcium
E) Vitamin E and sodium
This sounds like thyroid stormis it bicarb to offset metabolic acidosis???
8) An 80 y/o man is given a standard dose of midazolam and develops cyanosis, respiratory depression. An age-related increase in which of the following is the most likely cause:
A) Enterohepatic recycling
B) Metabolite formation
C) Plasma protein binding
D) Sensitivity to sedatives
E) Vd
I know its probably not C or E since that would decrease midazolamis it D???
9) What genetic mutation in tyrosine metabolism gives you albinism + ******ation??
10) Survival for an operation is
0-1 year: 62%
1-2 year: 80%
2-3 year: 84%
3-4 year: 85%
4-5 year: 76%
If a patient survives 2 years, the probability of surviving at least 4 years is:
a) 0.8
b) 0.85
c) 0.84 x 0.85
d) 0.62 x 0.8 x 0.84 x 0.85
e) 0.85-0.8
This question seems to come up again and again . I picked c but I suck at math! Am I right??
11) A 20 y/o F cries occasionally, feels sad, and doubts her ability to take care of her healthy 3d old newborn. She has started to breast feed and her sleep and appetite are normal. The most likely explanation for her feelings is:
a) Adjustment disorder with depressed mood
b) Brief reactive psychosis
c) Major depressive episode
d) Normal reaction to birth
e) Postpartum pituitary necrosis
A??? My second choice would be D???
For an alcoholic surgeon who comes to the OR drunk admits he has a problem, the best therapy is:
Alcoholics anonymous, an antidepressant, cognitive therapy for depression, or disulfiram
a) Adherens junction
b) Desmosome
c) Gap junction
d) Hemidesmosome
e) Tight junction
I have no idea
2) A 27 y/o female alcoholic with major depression tells the physician she has been repeatedly physically and emotionally abused by her partner. Appropriate response is:
a) Battering only grows worse with time. For your safety and self esteem it is in your best interest to leave this relationship.
b) Do you feel safe to go home?
c) Is there any way you can keep from getting him so angry?
d) There may be a correlation between your alcohol and the abuse. If you take steps to curb your alcoholism the abuse may subside
e) Why do you think your partner abuses you
A????
3) A study is done to determine if raloxifene prevents fractures. Results
Raloxifene: 138/2557 vertebral fractures (5.4%)
Placebo: 260/2576 vertebral fractures (10.1%)
How many women need to be treated with raloxifene to prevent one vertebral fracture?
a) 100/5.4 = 18.5
b) 100/10.1 = 10
c) 100/(10.1 + 5.4) = 6.5
d) 100/(10.1 5.4) = 21
e) 100/(10.1 x 5.4) = 2
D????
4) What antidiabetic causes orthopnea, pulmonary and peripheral edema, and an S3 gallop:
a) Acarbose
b) Glyburide
c) Metformin
D) Repaglinide
E) Rosiglitazone
5) The largest proportional increase in LV afterload and myocardial oxygen consumption occurs following a 20% increase in:
A) Aortic pressure
B) Coronary blood flow
C) Heart rate
D) Right atrial pressure
E) Stroke volume
In terms of increasing afterload, wouldnt it be A? But Im also thinking for myocardial oxygen consumption it would be C???
6) What causes brown kidney stones? There was nothing in the history, and the choices included hypercalcemia, hyperuricemia, and proteus infection (struvite). I looked these all up and couldnt find any particular color, so should I have gone with calcium since it is the most likely in terms of frequency?
7) A 30 y/o F undergoes thyroid resection because of CA. Within hours she develops neuromuscular excitability, severe cramping, laryngeal stridor, convulsions. TX is:
A) Intravenous bicarb
B) Vitamin A and K
C) Vitamin B6 (pyridoxine), B12, T3, and T4
D) Vitamin D and calcium
E) Vitamin E and sodium
This sounds like thyroid stormis it bicarb to offset metabolic acidosis???
8) An 80 y/o man is given a standard dose of midazolam and develops cyanosis, respiratory depression. An age-related increase in which of the following is the most likely cause:
A) Enterohepatic recycling
B) Metabolite formation
C) Plasma protein binding
D) Sensitivity to sedatives
E) Vd
I know its probably not C or E since that would decrease midazolamis it D???
9) What genetic mutation in tyrosine metabolism gives you albinism + ******ation??
10) Survival for an operation is
0-1 year: 62%
1-2 year: 80%
2-3 year: 84%
3-4 year: 85%
4-5 year: 76%
If a patient survives 2 years, the probability of surviving at least 4 years is:
a) 0.8
b) 0.85
c) 0.84 x 0.85
d) 0.62 x 0.8 x 0.84 x 0.85
e) 0.85-0.8
This question seems to come up again and again . I picked c but I suck at math! Am I right??
11) A 20 y/o F cries occasionally, feels sad, and doubts her ability to take care of her healthy 3d old newborn. She has started to breast feed and her sleep and appetite are normal. The most likely explanation for her feelings is:
a) Adjustment disorder with depressed mood
b) Brief reactive psychosis
c) Major depressive episode
d) Normal reaction to birth
e) Postpartum pituitary necrosis
A??? My second choice would be D???
For an alcoholic surgeon who comes to the OR drunk admits he has a problem, the best therapy is:
Alcoholics anonymous, an antidepressant, cognitive therapy for depression, or disulfiram
