the question is in the picture. basically the pt is polypharm + depression, and they ask what is the cause of the depression. the answer is propanolol. can someone tell me why ?
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nbme question need explanation for answer
- Thread starter shawnsf
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The whole passage is basically talking about beta blocker effects. BB are thought to cause depression and propranolol is the most common offender due to it is highly lipophilic.
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You need to know the toxicity for each drug and what JDUB mentioned above is bang on.
lipophilic = cross BB = CNS effects, they might not mention depression and something else so watch out for that.
Benzo= have the least SE from the psy drugs esp Barbiturates : usually resp depression
Digoxin= causes changes in the ekg such st segment scooping and yellow vision
Haloperidol = is a antipsycho which causes EPS (Parkinson symptoms)
Propranolol= causes depression (this is not mentioned in FA but i think was mentioned in UW)
Ranitidine= H2 blocker affects creatinine excretion
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