Need an ID-related journal club topic...

[GREGT]

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Something interesting and not something tired like "Zyvox vs. Vanc" or Ceftobiprole. Any ideas?

 

[Praziquantel86]

Validity of extended-interval dosing.

 

[GREGT]

A bit dry, but thanks...

 

[njac]

A bit dry, but thanks...

extended infusions of pip/tazo.

 

[bigpharmD]

therapeutic drug monitoring of voriconazole

 

[StaviZFingerZ]

Boring!!!!


Use of Colistin in MDR Gram Negs!!!!!


End of story.

 

[StaviZFingerZ]

A bit dry, but thanks...

yeah...like you could've done any better....

 

[StaviZFingerZ]

therapeutic drug monitoring of voriconazole

boring 👎

 

[StaviZFingerZ]

extended infusions of pip/tazo.

boring... 👎

 

[StaviZFingerZ]

Validity of extended-interval dosing.

boring..👎

 

[Requiem]

prophylactic macrolides in COPD to decrease exacerabations and inflammation

 

[njac]

Boring!!!!


Use of Colistin in MDR Gram Negs!!!!!


End of story.

Most of the places I interviewed had several pts on Colistin per month.

Meanwhile my home hospital isn't running into any carbepenemases yet. Yet.

 

[bigpharmD]

nebulized colistin vs iv antibiotics for the treatment of pneumonia

 

[Quiksilver]

HIV medication dosage adjustments in patients who require it due to D-D Interactions

 

[Praziquantel86]

boring..👎

Fine...

Plombage vs. linezolid for XDR-TB.

 

[StaviZFingerZ]

prophylactic macrolides in COPD to decrease exacerabations and inflammation

Boring 👎

 

[StaviZFingerZ]

Most of the places I interviewed had several pts on Colistin per month.

Meanwhile my home hospital isn't running into any carbepenemases yet. Yet.

Yet!! 👍

 

[StaviZFingerZ]

nebulized colistin vs iv antibiotics for the treatment of pneumonia

Ok, luke warm!

 

[StaviZFingerZ]

Fine...

Plombage vs. linezolid for XDR-TB.

You know how to perform Plombage?

 

[StaviZFingerZ]

HIV medication dosage adjustments in patients who require it due to D-D Interactions

😴 😴 😴

 

[rxlynn]

Something interesting and not something tired like "Zyvox vs. Vanc" or Ceftobiprole. Any ideas?

TX of HIV + patients with co-morbid MS

 

[Praziquantel86]

You know how to perform Plombage?

No, but I get the idea. Has anyone even done one in the last 50 years?

 

[p-rog]

Boring!!!!


Use of Colistin in MDR Gram Negs!!!!!


End of story.

nebulized colistin vs iv antibiotics for the treatment of pneumonia

I can't find any good new randomized control trials for this on pubmed. Am I looking in the wrong place?

 

[StaviZFingerZ]

I can't find any good new randomized control trials for this on pubmed. Am I looking in the wrong place?

Why do you suppose you can't find much info on this?

 

[p-rog]

Hm. I had assumed I was searching wrong, but I guess it's probably because it's too dangerous to do those kind of studies with active MDR infections.

 

[StaviZFingerZ]

Hm. I had assumed I was searching wrong, but I guess it's probably because it's too dangerous to do those kind of studies with active MDR infections.

no.

 

[p-rog]

Well then the only other logical option is that I can't find them because they don't exist!

(Yeah I know I'm wrong.)

 

[StaviZFingerZ]

Well then the only other logical option is that I can't find them because they don't exist!

(Yeah I know I'm wrong.)

lol!

I don't know if it exists or not. but I do know its happening. but just because we are doing it doesn't mean its published.

consider these 2 factors. colistin is an old drug. mdr gram neg is an emerging and recent phenomenon. so what does that mean?

 

[p-rog]

No pharma company funds to do the trials?


by the way, this is all I got:

http://www.medscape.com/viewarticle/498138

http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

http://www.medscape.com/viewarticle/497810

http://www.journals.uchicago.edu/doi/full/10.1086/432583?prevSearch=[title|any%3A+colistin+nebulized]&searchHistoryKey=

 

[StaviZFingerZ]

No pharma company funds to do the trials?

Why would pharma support a trial that doesn't benefit their drug? Colistin is an old drug..

 

[p-rog]

Right. That was my point.

 

[StaviZFingerZ]

Right. That was my point.

That could be one of the reasons. I do know of hospitals running an investigation with Colistin but I certainly doubt it's sponsored by Pharma.

Again, this may be a hard topic to research..that's why it's a good topic to dicuss..current and vital to ID arena today.