A career in nuclear medicine😉
Nuclear medicine is the branch of imaging that uses radio-isotopes to study the physiology and metabolism of the body (rather than the anatomy shown by x rays, computed tomography (CT), ultrasound, and magnetic resonance imaging (MRI)). Nuclear medicine today is the exciting development of the early 20th century pioneering work of, among others, Rutherford, the Curies, and Lawrence, who built the first cyclotron in 1933. With all the new isotopes and radiopharmaceuticals we now have available, there is huge scope for advances in the field. If you are the sort of person who would enjoy the challenge of working in a rapidly developing multicraft specialty, then you may well be a candidate for a national training number (NTN) in nuclear medicine. It also helps to be computer literate. There have been many recent advances in nuclear medicine, but without doubt the most exciting is the development of positron emission tomography (PET) imaging, and in particular PET/CT. This has revolutionised oncological imaging, and ideally no major cancer centre should be without PET.
Today, nuclear medicine encompasses a wide range of investigations and treatments.
Nuclear medicine, being essentially physiological, correlates well with all other forms of imaging, which are mainly anatomical. We can show the activity of disease rather than the anatomical appearance. For example, in Crohn's disease the barium enema will show what the bowel looks like, but the labelled white cell scan will show the extent of activity. It's a vital tool for the clinician. There is therefore a huge interaction with the rest of imaging, the clinicians and the oncologists. Box 1 shows a typical week in nuclear medicine.
Box 1: A typical week in nuclear medicine
Reporting all types of scans
Carrying out cardiac stress studies
Pretreatment clinics for thyrotoxic patients and for other treatments
Administration of treatment--for example, radio-iodine
Taking part in multidisciplinary teams
Teaching
Research and development
Other hospital committee work
Possibility of continuing radiology or general medicine work
Nuclear medicine treatment
You can also become involved in the therapeutic aspects of nuclear medicine, both curative as in the treatment of thyrotoxi-cosis with 131I, neuroendocrine tumours with yttrium and 131I, and palliative as in the administration of strontium or samarium to alleviate pain from bone metastases. In many centres, treatment of thyrotoxicosis with radio-iodine is the preferred option, and has excellent results. Nuclear medicine treatment offers the possibility to target neuroendocrine tumours, such as carcinoid, selectively and research is continuing to label specific monoclonal antibodies to various tumours both for diagnosis and treatment.
Nuclear medicine scans can be either static or dynamic, thus showing differing aspects of the body's function (box 2).
There is no doubt that the future lies with PET scanning. PET uses 18F labelled fluoro-deoxyglucose, a glucose analogue, to map the metabolic function of cells. This, when combined with modern CT, gives a most powerful weapon in the staging of malignancy.
PET is also useful in cardiac imaging to define hibernating myocardium, and in neurological imaging, particularly of dementia.
Box 2: Scans reflecting differing aspects of the body's function
Static
Bone
Thyroid
Lung scan
DMSA renal
PET
Dynamic
MAG3 renal
Cardiac
Job appeal and satisfaction
For all the reasons I have given, nuclear medicine can be a very satisfying career (box 3)
The satisfaction often comes from clarifying a diagnosis which is not clear clinically, such as pulmonary embolism. Your images alter the patient's treatment for the better. Nothing beats letters of thanks from patients you have helped or cured.
Box 3: Appeal of nuclear medicine
Intellectually very satisfying as part of a multicraft team
Intensive work
Good correlation with radiology and general medicine
Research involvement in all studies requiring an ARSAC licence
Friendly colleagues within nuclear medicine world
Job sharing possible
Good balance between work and life
The future
This is bright and good for nuclear medicine specialists. Without doubt, the future is CT/PET, as cancer and oncology enjoy a high priority. Nuclear medicine can and does have a vital role in both diagnosis and therapy, and you can be part of it.
Plan to visit your local nuclear medicine department, talk to the staff there, and see if you have what it takes.