- Joined
- Apr 29, 2011
- Messages
- 2,171
- Reaction score
- 863
Is the first step in the mechanism pH dependent?
As in:
If acidic conditions, protonate the oxygen from the carbonyl first.
If basic conditions, have the nucleophile attack the carbonyl first.
As in:
If acidic conditions, protonate the oxygen from the carbonyl first.
If basic conditions, have the nucleophile attack the carbonyl first.