Oliceridine

[nimbus]

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Anybody get a chance to play with this? Novel “biased opioid” with a better side effect profile.

Oliceridine- Opioid of the 21st Century - PMC

Oliceridine (Olinvyk® Trevena, PA, USA) was approved by the United States Food and Drug Administration for clinical use on Aug 8, 2020. Even though, the indication of its approval is very restrictive (to manage moderate-to-severe acute pain in ...

www.ncbi.nlm.nih.gov

 

[coffeebythelake]

Anybody get a chance to play with this? Novel “biased opioid” with a better side effect profile.

Oliceridine- Opioid of the 21st Century - PMC

Oliceridine (Olinvyk® Trevena, PA, USA) was approved by the United States Food and Drug Administration for clinical use on Aug 8, 2020. Even though, the indication of its approval is very restrictive (to manage moderate-to-severe acute pain in ...

www.ncbi.nlm.nih.gov

So what is its abuse potential??

 

[nimbus]

So what is its abuse potential??

Probably very high but it may be less likely to cause respiratory arrest.

 

[coffeebythelake]

Probably very high but it may be less likely to cause respiratory arrest.

Exactly what is needed 🙄... and When they switch from this to the usual opioids of abuse they OD quickly

 

[PainDrain]

Probably very high but it may be less likely to cause respiratory arrest.

Where is the fun in that?

 

[Hoya11]

Anybody get a chance to play with this? Novel “biased opioid” with a better side effect profile.

Oliceridine- Opioid of the 21st Century - PMC

Oliceridine (Olinvyk® Trevena, PA, USA) was approved by the United States Food and Drug Administration for clinical use on Aug 8, 2020. Even though, the indication of its approval is very restrictive (to manage moderate-to-severe acute pain in ...

www.ncbi.nlm.nih.gov

its an interesting idea

im not sure you can truly separate the analgesia and the psychological high, maybe in decades of research. i dont think we are close to being able to do that right now, and this is much more likely another money grab by opioid pharma

 

[LaminaV]

Nalbuphine, buprenorphine, now olicerdine… this g-protein mediating drug will be welcome in the pain world . Hopefully in an oral form someday .