Are palindromic peptides considered unique or the same? For example, would Gly-Gly-Gly-Ser be considered the same molecule as Ser-Gly-Gly-Gly or would they be classified as two different polypeptides?
Are palindromic peptides considered unique or the same? For example, would Gly-Gly-Gly-Ser be considered the same molecule as Ser-Gly-Gly-Gly or would they be classified as two different polypeptides?
I believe (not 100% sure) they would be considered unique due to directionality -
Eg: If you have (N-terminus)-Gly-Gly-Gly-Ser-(C-terminus) it would be different from (N-terminus)-Ser-Gly-Gly-Gly-(C-terminus).
Edit: Whiteshadow beat me to it!
I think first of all, you'd never have an amino acid chain that short. Secondly, I think if it was something like you have, the fold would indeed be very very similar giving rise to two oligopeptide chains that would have a relatively similar shape.
But yea, remember palindromes are definitely important when considering DNA in terms of restriction enzymes finding the correct sequence to cleave.
That's the only case I can remember palindromic things being important, any one have any?!!?
If I'm remembering correctly, I think that's for DNA, not proteins/amino acidsIt's been a while since I've taken genetics, but I also remember palindromic sequences being important in transposons and conjugation? I'm pretty sure that all this is way beyond the scope of the mcat though..
I think first of all, you'd never have an amino acid chain that short. Secondly, I think if it was something like you have, the fold would indeed be very very similar giving rise to two oligopeptide chains that would have a relatively similar shape.
But yea, remember palindromes are definitely important when considering DNA in terms of restriction enzymes finding the correct sequence to cleave.
That's the only case I can remember palindromic things being important, any one have any?!!?
If I'm remembering correctly, I think that's for DNA, not proteins/amino acids
not to be an ass, but just because you can't think of it doesn't mean it doesn't happen and doesn't mean its not important. and you can have peptide sequences as short as 2 amino acids, ever heard of solid-phase synthesis? there are palindromic sequences in proteins, and you can certainly have multiple applications of short palindromic sequences. you can pubmed palindromic protein and find tons of examples, i'll leave that to you. science is a huge, wide, and open field, don't be too narrow minded.
I think first of all, you'd never have an amino acid chain that short. Secondly, I think if it was something like you have, the fold would indeed be very very similar giving rise to two oligopeptide chains that would have a relatively similar shape.
But yea, remember palindromes are definitely important when considering DNA in terms of restriction enzymes finding the correct sequence to cleave.
That's the only case I can remember palindromic things being important, any one have any?!!?
zwander said:It funny when people say....