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I have a pharmacy math proficiency exam coming up. Please help! Thanks. Sorry if my work is hard to read. I couldn't format the way I wanted to.
1) A high dose treatment of osteosarcoma includes the use of methotrexate at starting dose of 12 g/m^2 as a 4-hour intravenous infusion. For a patient having a BSA of 1.7m^2 and weighing 162 lbs, calculate the dose on the basis of mg/kg/min. (Answer is 1.15 mg/kg/min)
I multiplied the 12g/m^2 and 1.72 m^2 and got 20.64 g. I don't know what to do from there.
2) Atrovent nasal spray contains 0.03% of ipratropium bromide in a 30 mL metered dose container. If the container is calibrated to deliver 345 sprays, calculate the volume of each spray, in microliters, and the medication content of each spray, in micrograms (Answer: 86.96 and 26.09 micrograms)
I don't know how to do this one! 😡
3) A starting pediatric dose of DILANTIN sodium is 6 mg/kg/day, administered in three equally divided doses. Using tablets containing 50 mg of phenytoin sodium, a pharmacist prepared a suspension such that each 1 mL, delivered from a calibrated dropper, contained a single dose for a 44 pound child. How many tablets should be used to prepare 30 mL of the suspension? (Answer is 24 tablets)
I did
6 mg x
------ = ---- with x = 120 mg
2.2 lbs 44 lbs
Then I did:
120 mg x
----------- = ---- with x = 3600 mg
1 mL 30 mL
Then I did:
3600 mg x 1 Tablet
---------- = 72 tablets (wrong of course)
50 mg
4) How many mg each of REGLAN. ATIVAN, and COMPAZINE are contained in each mL of the injection? (Answers: REGLAN = 1.13, ATIVAN = 0.0075, COMPAZINE = 0.075)
REGLAN (5 mg/mL) 30 mL
ATIVAN (2 mg/mL) 0.5 mL
Mannitol, 25% 50 mL
COMPAZINE (5 mg/mL) 2 mL
Dextrose Injection, 5% 50 mL
(For REGLAN, I did:
5 mg x
------- = ----- with x = 150 mg
1 mL 30 mL
Then I did:
150 mg x
--------- = ------- with x = 3 mg (wrong answer)
50 mL 1 mL
1) A high dose treatment of osteosarcoma includes the use of methotrexate at starting dose of 12 g/m^2 as a 4-hour intravenous infusion. For a patient having a BSA of 1.7m^2 and weighing 162 lbs, calculate the dose on the basis of mg/kg/min. (Answer is 1.15 mg/kg/min)
I multiplied the 12g/m^2 and 1.72 m^2 and got 20.64 g. I don't know what to do from there.
2) Atrovent nasal spray contains 0.03% of ipratropium bromide in a 30 mL metered dose container. If the container is calibrated to deliver 345 sprays, calculate the volume of each spray, in microliters, and the medication content of each spray, in micrograms (Answer: 86.96 and 26.09 micrograms)
I don't know how to do this one! 😡
3) A starting pediatric dose of DILANTIN sodium is 6 mg/kg/day, administered in three equally divided doses. Using tablets containing 50 mg of phenytoin sodium, a pharmacist prepared a suspension such that each 1 mL, delivered from a calibrated dropper, contained a single dose for a 44 pound child. How many tablets should be used to prepare 30 mL of the suspension? (Answer is 24 tablets)
I did
6 mg x
------ = ---- with x = 120 mg
2.2 lbs 44 lbs
Then I did:
120 mg x
----------- = ---- with x = 3600 mg
1 mL 30 mL
Then I did:
3600 mg x 1 Tablet
---------- = 72 tablets (wrong of course)
50 mg
4) How many mg each of REGLAN. ATIVAN, and COMPAZINE are contained in each mL of the injection? (Answers: REGLAN = 1.13, ATIVAN = 0.0075, COMPAZINE = 0.075)
REGLAN (5 mg/mL) 30 mL
ATIVAN (2 mg/mL) 0.5 mL
Mannitol, 25% 50 mL
COMPAZINE (5 mg/mL) 2 mL
Dextrose Injection, 5% 50 mL
(For REGLAN, I did:
5 mg x
------- = ----- with x = 150 mg
1 mL 30 mL
Then I did:
150 mg x
--------- = ------- with x = 3 mg (wrong answer)
50 mL 1 mL
