Primary Authorship in a peer reviewed paper... how do you guys do it?...

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misplacedshadow

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Greetings Guys,

I graduated in may and was able to land a volunteer research position at a medical college. I will have a publication at a peer reviewed journal but I will be 4th or 5th author. I really want to come up with my own experiment and conduct it so I can publish it as a primary author. Those of you that were able to accomplish this, can you please sheds some light on how you achieved this?
 
Talk to your PI. Ask if there is a side project that you can pick up. Run with the project from start to finish. Collaborate with your PI in publishing it. Though you could feasibly be a 1st author your PI will most likely need to put his/her name on it as well in order for it to be accepted by the journal.
 
There was a thread recently that included discussions about being first author in a paper. You should search for this kind of stuff because it's a common topic.

http://forums.studentdoctor.net/search.php?searchid=16787567

http://forums.studentdoctor.net/showthread.php?t=846313

Basically (summarizing the 150 threads I've read about this), being published 1st author is mostly luck in getting a PI that will allow you to do so and super hard work/determination in designing a publishable experiment and seeing it through/writing it up from start to finish at a level that will survive the peer-review process. There's so few people that publish 1st author as an undergrad that any advice is hardly going to be horribly weakened by the sample size.

Very few applicants have 1st author publications and being published at all already puts you in the upper echelon of research candidates. Anything more (a 1st author pub) will not really help your chances of admissions. It's like MCAT, getting a 43 vs a 40 doesn't really matter (even though it looks better) because by that point you're already so accomplished that the difference between the two is probably nothing more than some fluke differences in mindsets that day, a few guesses that happened to go your way, etc.

I'm not saying there's anything wrong with shooting for a 1st author, but simply know that it's difficult to just follow the blueprint set by others that have published 1st author since it's too dependent on you being lucky enough to have a PI that supports undergrads publishing as 1st authors and having enough time/guidance to produce results that are publishable (it takes some grad students years of full-time work to publish 1st author).
 
Talk to your PI. Ask if there is a side project that you can pick up. Run with the project from start to finish. Collaborate with your PI in publishing it. Though you could feasibly be a 1st author your PI will most likely need to put his/her name on it as well in order for it to be accepted by the journal.

You'd still be considered first author even if your PI is on it. Even if you did the science, you're using the PI's lab/grantmonies/etc.

Yeah and try not to beat yourself up over getting the first author publication, as it's going to be a long road if that's your primary motivation. I recall one grad student who was a bit of an egotistical douchecanoe nearly assplode in anger because people he deemed as stupid were getting JACS pubs before him. It's just the way the cookie crumbles sometimes.
 
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You'd still be considered first author even if your PI is on it. Even if you did the science, you're using the PI's lab/grantmonies/etc.

Agreed. I was just noting this for pragmatics.

Edit: Sorry n3xa, didn't mean to edit your post... I was trying to quote it and clicked the wrong button 😳
 
You'd still be considered first author even if your PI is on it. Even if you did the science, you're using the PI's lab/grantmonies/etc.

Any student papers published in a PI's lab will have that PI listed as last author (although location may differ in some disciplines). When you go up for tenure, both the number of first-author and last-author pubs you have is important.
 
Any student papers published in a PI's lab will have that PI listed as last author (although location may differ in some disciplines). When you go up for tenure, both the number of first-author and last-author pubs you have is important.

To make it even more confusing, you may be listed first person in the title (making you the first author), but often the last author (i.e. the PI) will be listed as the corresponding author, which effectively was put into place as a way of letting proteges get credit for work but keeping the research centralized around the PI.
 
Small labs where you're not competing with graduate students or postdocs for publication rank are usually a good starting point. In vitro work is usually a much safer bet than animal studies, but it is by no means a slam dunk. But, as most people have stated, it's mostly luck, time, and a lot of work.
 
Agreed. I was just noting this for pragmatics.

Edit: Sorry n3xa, didn't mean to edit your post... I was trying to quote it and clicked the wrong button 😳

LOLOLOLOLOL 😛

Any student papers published in a PI's lab will have that PI listed as last author (although location may differ in some disciplines). When you go up for tenure, both the number of first-author and last-author pubs you have is important.

Trufax, right here. I also speak from a synthetic organic POV, where we typically have less names on a paper compared to some of those biology papers. 😱 And I was lucky to never really have to personally deal with the whole who-gets-mentioned cos it does sometimes get messy.

As long as you enjoy what you do, can explain the science and your role on the project, you'll be fine OP. Good luck in the lab!
 
yeah, first author is great, but it's largely luck. Not to mention, we could go on for days about which journal you publish in...Science vs Nature vs Cell vs PNAS....PLOS...lol. I think what usually helps is having a PI that produces good work, serves as a good mentor, and is willing to let you work independently. If you're lucky, you'll get to be an author. If you're really lucky, you'll become first author. And, a lot of PIs will tell you you can become an author...but it's a LONG LONG road ahead.

Sometimes PIs will use it as a selling strategy: how else are you going to keep undergrads in their labs?
 
Agreed. I was just noting this for pragmatics.

Edit: Sorry n3xa, didn't mean to edit your post... I was trying to quote it and clicked the wrong button 😳

Can't even figure out your mod powers. Tsk, tsk.



(I have nothing to contribute to the conversation, I just wanted to make fun of Saggy. 😀 )
 
Sometimes PIs will use it as a selling strategy: how else are you going to keep undergrads in their labs?

:meanie:

Yeaaaaaaah totally fell for that one ten years ago!

🙁
 
I have two first author publications in the Journal of Cardiothoracic Surgery, I'm going to be a senior in undergrad applying this cycle.
 
I have two first author publications in the Journal of Cardiothoracic Surgery, I'm going to be a senior in undergrad applying this cycle.

That's wonderful and we're all very proud of you, but that did nothing to address the OP's question on how one goes about first authorship.
 
That's wonderful and we're all very proud of you, but that did nothing to address the OP's question on how one goes about first authorship.

Everything that has been stated above is 100% true. I work with the chief of surgery who already has like 300+ publications and doesn't care at all if he's first author because he knows it's 1000x more meaningful and helpful to me right now than it is to him.
 
I have two first author publications in the Journal of Cardiothoracic Surgery, I'm going to be a senior in undergrad applying this cycle.

And you should be very proud of that journal's <1.0 impact factor.

Edited to add:
Although, really this isn't something undergrads should worry about. But your utter lack of a helpful contribution brings out the snarkiness in me.
 
I graduated in may and was able to land a volunteer research position at a medical college. I will have a publication at a peer reviewed journal but I will be 4th or 5th author. I really want to come up with my own experiment and conduct it so I can publish it as a primary author. Those of you that were able to accomplish this, can you please sheds some light on how you achieved this?

First, be grateful for authorship you have. You are a volunteer research position, which may or may not mean much to the lab. Be thankful for what you got.

Second, unless you are talented, the lab is going to be hesitant about you running your own experiment. In order to do that, you have to do tons of reading and check to see if what you suggest has not been done before - otherwise, you are wasting valuable money of the lab. So often times, you come down to ask questions to the other members in the lab, who guide you in the direction that you want, and they actually contribute more than you, who end up just micropipetting liquids into tubes.

Lastly, you are missing a huge portion of publication for 1st/2nd author, which is on writing the manuscript. Have you had an experience writing a manuscript for publication? And no, lab reports don't count. Writing manuscript takes tons of time, so I really doubt that it's feasible for someone who's just volunteering in a lab.
 
And you should be very proud of that journal's <1.0 impact factor.

Edited to add:
Although, really this isn't something undergrads should worry about. But your utter lack of a helpful contribution brings out the snarkiness in me.

I know I shouldn't laugh... but that totally made me LOL.
 
Impact madness! LOL. just for funn...

I'll take my 5th author in Science over your two 1st authors in JCS! lol

I wonder what adcoms would more highly at...lolz.

On a more serious note, it's really luck based. You really need a PI that believes in you, gives you a publishable project, and will help you through the publication process. Not having one of these i think exponentially reduces your chances of getting authorship, esp first author.

So, that being said, how do you do it?
1) Work in a lab for a while, and develop your relationship with the PI. Unless you're just a genius (in which case I think you're in the wrong forum...lol. you should just get a PhD instead, why MD?!?! LOL), you probably won't make a whole lot of headway to publish. It's possible, but not very often. besides, not many phd rotation students publish their rotation projects anyway...lol

2) Occasionally bring up if there's something more you can do, or ask where the research is headed.

3) Don't be a dick. Work well with people in lab, so even if you don't get first author, you'll be able to work with other people on their projects, and they will be MUCH MORE inclined to help you on yours, especially on the first author project, so to speak. Not to mention if you make a substantial contribution, you'll have more opportunities to chip in for a secondary authorship =P

4) Start thinking of your own expts, and ask your PI about experimental questions you have. Start to think of questions you want to explore in the lab. For example, I worked with nematodes and aging pathways...I was looking at genes that affect aging, looking at unfolded protein stress, and while I was UV crosslinking some plates, I had the thought of UV as a stressor, so I asked the PI about working on a UV-stress aging pathway. He liked the idea, and put me through. This is a way to start looking at independent projects for yourself.

and above all, HARD WORK IS CRITICAL. Hope this helps.
 
I think adcoms could care less about impact factor. A first author pub is probably better because it IMPLIES the author has contributed more to the publication.

Even for academic residency programs i'm not sure impact factor is that important compared to field relevance.
 
I think adcoms could care less about impact factor. A first author pub is probably better because it IMPLIES the author has contributed more to the publication.

Even for academic residency programs i'm not sure impact factor is that important compared to field relevance.

Yeah, that's what I was thinking too. lots of field related stuff isn't published in the higher impact journals anyways...

But pubs are still a crapshoot. i dunno, kinda sucks cuz there's a lot of people who work really hard but still don't have any pubs from their labs...
 
Impact madness! LOL. just for funn...

3) Don't be a dick. Work well with people in lab, so even if you don't get first author, you'll be able to work with other people on their projects, and they will be MUCH MORE inclined to help you on yours, especially on the first author project, so to speak. Not to mention if you make a substantial contribution, you'll have more opportunities to chip in for a secondary authorship =P

and above all, HARD WORK IS CRITICAL.


Couldn't agree more. The worst thing anyone can do is to be enemies with the grad students. If they aren't willing to teach you anything then you won't be able to do anything. Also grad students like to talk, a lot, so you have one shot to get on their good side or else everyone will dismiss you (I've seen it happen and its not pretty).

Here are just some observations that I have seen. Take them simply as a single observer's point of view, but they are pretty simple.

1). If a lab has not published in the past 3-5 years, then it probably won't publish anything while you are there.

2). Follow the money. If a lab is getting new funds then the PI is probably onto something and will be willing to spend money to try and produce results.

3). Professors who are new and are trying to get tenure will be very willing to let undergrads have responsibilities that are not normally given to undergrads. The PI will be desperately trying to publish (so you know papers will be coming) and the PI usually has to train the grad students and is normally more than willing to train undergrads as well.

4). Know the material. It doesn't take too much to sit down and get a rough understanding about whats going on in the lab. Having an understanding and being able to contribute maybe a comment or two in group meeting will go a long ways towards establishing trust (must be ligit contributions, nothing will sink your ship faster than stupid comments).

5). Be seen but not heard. Its best to just absorb whats going on around you when you start in a lab. (Once again it all goes back to the trust between you and the grad students or PI). Generally undergrads will not have much to add if they are just starting in a lab. Get a feel for what is expected, then start to add to conversations. Once again Don't Be a Dick, grad students (in general) hate undergrads and being a dick will only further cement that hatred.

6). Work your butt off. Plain and simple, if you show up early in the morning and work late then you will gain respect.

7). Always have something to do. Don't sit around and read ESPN or SDN while in lab, that looks really bad. Either be working on your project, find something to clean, or be reading scientific articles that are relevant.

8). If you really want to get published find a specific area that your group is working on that you can specialize in. For example, if your group has to learn how to do a specific assay and no one is really sure how to do it (or if there is something that is going wrong and no one knows why), then you take initiative and try to learn how to do the assay (or whats going wrong) by reading journals, talking to other groups. If you show initiative, then the people in your group will trust you with more and more things.

9). Just as Rome wasn't built in a day, so to you will not become king of the lab (to borrow a term from "Bones") over night. It takes time, but each day inch closer and closer to your goal by building trust and showing responsibilities.

10). Focus on what has been given. I ran across an article (maybe it was here on SDN or elsewhere) but it said that often those who want more responsibility in life often are not taking care of the things that they are responsible for. An example that I have seen: an undergrad wanted more responsibility and he was confused why he wasn't able to get more work (more involved) in lab. Well ends up that the guy had been asked to order paper for the printer (pretty petty task), well he never did and after a week of having no paper the grad students ordered it themselves, needless to say he was not given more responsibilities.

11). Don't kiss ass. There is nothing that grad students hate more than an undergrad kissing the PI's ass and going over their heads. Judge how the grad students interact with the PI and go from there. Some groups go get beers with their PI; in other groups, the PI will be in lab 15 minutes a week and thats all the contact that they have with the grad students. Just use judgement on when to go to the PI, sometimes its necessary or beneficial, but not normally.

12). Know what you are doing. The final thing I will say about gaining trust is know why you are doing something. If you are using a mass spec machine, you should probably know why you are using it, if or what kind of separation you are using and why. Example: I was shadowing a friend in her lab and I was asking her some questions about what she was doing and why she was using this chemical as opposed to another (I was trying to learn the technique not throw her under the bus) and she had no idea on any of these simple "science" questions, and her PI was standing right there and had a look of horror on his face. So simply, don't horrify your PI by not knowing what you are doing.

12*). Just a note, even if you are not getting paid for your work that does not mean that you are not costing the lab money. Because depending on what materials you are using, you can be really blowing through money just in materials and so if you screw up you could potentially lose the lab thousands of dollars.

13). How do you find a good lab (I come full circle). A great way is to ask a trusted elderly science professor. Typically (and I say typically realizing that this is not the case always) elderly professors will not be as heavily involved in their own research but they will have an ear to the ground as to what is going on in each lab. If you know this elderly professor well (or any professor) you should go to them and ask them, who is doing good research and where could I get significant research experience.

13*). (I know that I will get no award for brevity, so I will continue in my thesis). Research experience >>> first authorship. Now let me explain this. If you are looking towards getting into medical school or MSTP or MD/PhD then you might (if MD/PhD then you will) be asked about your research. Now if you say, "I was first author" (or 2nd or 4th or whatever) and they ask, "Oh could you explain your project and how you contributed?" And if you respond with "oh, well I mainly did grunt work, but I was Nth author, look." Then you are toast. Its much better to go into those interviews being able to say, I was given these responsibilities (actual research experience) but I not fortunate enough to get a publication, then the interviewers will look much more favorable upon this. You can get publications and be in lab 3 hrs/ week while others can be working 30 hrs/week and never get a pub. (Life isn't fair, this is why everyone says its luck because it is) And whats even more important than just know techniques (because even monkeys can learn techniques) is learning what questions need to be asked and how one goes about answering those questions <----- most important thing to learn in research.

I think I'm on 14). Now here is something I am unsure about so take this with a grain of salt. (Any comments would be gladly accepted on this issue). There will be lab drama. There always is. Grad student X hates undergrad Y and threatens to kick him out. Or PostDoc Z gets on everyones' nerves and Grad Student J calls them out on it. Whatever the case, it will happen. Its best to be as neutral as possible in whatever situation, but of course thats not always possible. DONT PLAY BOTH SIDES, this will bite you in the ass because "grad students always talk" and you will be found out. So keep your head down when possible.

14*). Also related to this, is the blame game. Things go wrong and PI or PostDocs or Grad students have to blame someone. The last thing that you should do is point figures (its just not professional). If your PI comes to you and is telling you that you completely screwed up the experiment because some concentration was wrong (even though it was the other undergrad) sit there and take it and then afterwards go and talk with the other undergrad. (Sounds stupid, but the PI will trust you more because you were willing to be corrected and as long as you are humble and promise to do it right next time then he will trust you more; also the other undergrad will be thankful to you for not ratting him out and others in your lab will see what happened and the will know whose fault it really is and things will trickle up (maybe not specifically that situation but character traits) to the PI)).

(I've noticed that these paragraphs keep getting longer and I use too many parenthesis) (Also by the time that I finish this post, this thread will be on the 3rd page) But I'm on a roll so I will continue <most of the bad things that have happened have happened to me, so I'm trying to share my knowledge so that others don't have to go through these thing> Also I'm still in the general area of telling how to get publications.

15). Rule 1 for when you are looking at a new lab to perhaps join. If all the grad students are foreign then there is a chance that the PI works the students awfully hard. (Not so sure how true this is but this is what I have been told by my grad students and others). So investigate a little if everyone is foreign to makes sure you are not getting into an environment that might not be the best for you.

16). Now I've talked quite a bit about labs where there are grad students and post docs, but there are labs where there are no grad students just the PI and undergrads. Now these labs can go two ways: 1) The PI is heavily involved or 2) the PI is not involved. I will speak to the first and comment on the second later. When the PI is heavily involved this can be very good and a great learning experience. The PI will take time to teach you protocol and techniques and if you show interest your responsibility can increase. This is an excellent place to learn about "What question ought to be asked and how to answer those questions" because you can ask the PI, why are we doing this or what made you choose this chemical instead of that chemical. [Just a note on these labs, you need to be careful that the PI is not simply using the undergrads for sheer grunt work. I have seen several who only have undergrads do mindless, repetitive work which is great but learning is not taking place].

Keys to striving in these labs are hard work and following the instructions of the PI to the letter. Since the PI is the only one above you, it is key to gain his trust.

Now as to labs where the PI is hands off without grad students. These are tricky labs. They can be great, they can be horrible. These labs will generally have an upperclassman who "oversees" the lab. (I have no idea how many of these actually exist but this probably applies to all hands-off labs) These labs are really tough to screw up but also really tough to accomplish much in. In general I think these are excellent labs to learn how to "think for yourself" in. But these are labs where you can display leadership (and once you are the "overseer," dealing with everyone's problems). Generally these labs will not turn out the most research papers but these can be excellent places to gain experience.


Now since I love rankings I will put some rankings out (note these are just from my experiences which is limited to one school and the stories that I have read here on SDN) (*These are only meant as a rough guide, to truly understand a lab, nothing replaces your own background checks).

Most likely to be producing papers:

1. Young teachers (on tenure track) w/ grad students
T2. Tenured teachers w/ grad students
T2. Teachers (on tenure track) w/o grad student but PI is involved
4. Teachers (not on tenure track) w/o grad students but PI in involved
5. Teachers (not on tenure track) w/o grad students and PI is NOT involved

Mostly likely for student to be ignored:

1. Tenured teachers w/ grad students
2. Teachers (not on tenure track) w/o grad students and PI is NOT involved
3. Young teachers (on tenure track) w/ grad students
4. Teachers (not on tenure track) w/o grad student but PI is involved
5. Teachers (on tenure track) w/o grad students but PI in involved

Most room for "aggressive expansion" (to quote the joker):

1. Young teachers (on tenure track) w/ grad students
2. Teachers (on tenure track) w/o grad students but PI in involved
3. Teachers (not on tenure track) w/o grad students and PI is NOT involved
4. Teachers (not on tenure track) w/o grad student but PI is involved
5. Tenured teachers w/ grad students

Best Environment for a Go Getter, A self Motivated person (these people will feel stifled by grad students or PIs watching over their shoulder):

1. Young teachers (on tenure track) w/ grad students
2. Teachers (not on tenure track) w/o grad students and PI is NOT involved
3. Teachers (on tenure track) w/o grad students but PI in involved
4. Teachers (not on tenure track) w/o grad student but PI is involved
5. Tenured teachers w/ grad students

Best Environment for Students who like step by step instructions and are very by the book (there is nothing wrong with these people they will make great doctors) (they will feel completely lost and will become ignored in large labs where they might be tossed to the wind):

1. Teachers (on tenure track) w/o grad students but PI in involved
2. Teachers (not on tenure track) w/o grad student but PI is involved
3. Tenured teachers w/ grad students
4. Young teachers (on tenure track) w/ grad students
5. Teachers (not on tenure track) w/o grad students and PI is NOT involved <Stay away from this lab, you will drown>

Closing words of advice:

Don't feel bad sometimes it is best to move on from one lab to another.

Finding out which type of lab will help you be the best that you can be which will lead to publications or significant research experience or both!

Make sure that the lab can have side projects. If the lab only uses one machine and the machine is always being used, then you could sit and do nothing. (I had a friend who had this happened to him, he had fun sitting doing nothing 40hrs/week all summer).

If you dont like the subject then you wont like the research and you wont work hard and you wont get published. Start with what you like and work from there (I understand small schools and this is not always possible but PIs at smaller schools are a little bit more willing to work with you so that you are interested in the research)

Oh, the first week always sucks. Just gut through it, it will get better.

Bench research is not for everyone, you dont have to love it. You can go to your med school interview and they ask you about your research and if you explain it and then volunteer the information that you did not enjoy it, the interviewer will not look down on you for this but will respect your life decision because bench research is not for everyone. But with this being said, bench research is only one type of research and if you hate bench research then you won't necessarily hate all research. So its ok to close the door to bench research but don't be naive and close the door to all research.

Well, I should end my treaties here. I apologize for my brevity (PM me if you would like me to expand on any subject, I don't want to burden this wall anymore). (The brevity thing above is a joke). Finally, I once again state that these are simply my observations and should be taken as observation and helpful words of advice not as set in stone law. I myself have worked in a lab with a young PI (on tenure track) with grad students and in a lab of a tenured PI w/o grad students and he was not involved. I have shadowed quite a few labs and seen how other labs work, but do not claim all knowledge in those other labs. Also, every lab, every university is different and these rules could be completely null in some places, but I doubt that hard work and politeness will fail you. I myself have 3 first author papers and am working on more (I saw this not to brag but to simply give credence to what I saw). However, I have only finished two years of undergrad and thus anything about medical school is what I have been told by trusted sources who could be wrong but I have only tried to pass on credible information. I hope that this is helpful to anyone who is interest and I apologize for any typo's its 3 a.m. at this point in time.

Wow 7 pages in Microsoft word (I have said too much!)
 
I have two first author publications in the Journal of Cardiothoracic Surgery, I'm going to be a senior in undergrad applying this cycle.

According to one ranking service, JCTS is the second worst journal in all of cardiac research, right below something called "Netherlands Heart Journal" and above the "Hellenic Journal of Cardiology". I actually don't know what the Hellenic Journal of Cardiology is. Incidentally, July 2011 was the first month that HJC was even awarded an impact factor, so your stay as only the second worst journal in the entire field may soon come to an end. Serious question: Is JCTS even peer reviewed? It is, of course, but I did not think it was even possible to publish like this in the United States. There is probably a good reason your PI is letting you take first author on this one...
 
According to one ranking service, JCTS is the second worst journal in all of cardiac research, right below something called "Netherlands Heart Journal" and above the "Hellenic Journal of Cardiology". I actually don't know what the Hellenic Journal of Cardiology is. Incidentally, July 2011 was the first month that HJC was even awarded an impact factor, so your stay as only the second worst journal in the entire field may soon come to an end. Serious question: Is JCTS even peer reviewed? It is, of course, but I did not think it was even possible to publish like this in the United States. There is probably a good reason your PI is letting you take first author on this one...

Nice investigative journalism 👍

(pun intended)
 
Congratulations, this is the longest post I've ever seen in 5 years on sdn... :bow:


Impact madness! LOL. just for funn...

3) Don't be a dick. Work well with people in lab, so even if you don't get first author, you'll be able to work with other people on their projects, and they will be MUCH MORE inclined to help you on yours, especially on the first author project, so to speak. Not to mention if you make a substantial contribution, you'll have more opportunities to chip in for a secondary authorship =P

and above all, HARD WORK IS CRITICAL.


Couldn't agree more. The worst thing anyone can do is to be enemies with the grad students. If they aren't willing to teach you anything then you won't be able to do anything. Also grad students like to talk, a lot, so you have one shot to get on their good side or else everyone will dismiss you (I've seen it happen and its not pretty).

Here are just some observations that I have seen. Take them simply as a single observer's point of view, but they are pretty simple.

1). If a lab has not published in the past 3-5 years, then it probably won't publish anything while you are there.

2). Follow the money. If a lab is getting new funds then the PI is probably onto something and will be willing to spend money to try and produce results.

3). Professors who are new and are trying to get tenure will be very willing to let undergrads have responsibilities that are not normally given to undergrads. The PI will be desperately trying to publish (so you know papers will be coming) and the PI usually has to train the grad students and is normally more than willing to train undergrads as well.

4). Know the material. It doesn't take too much to sit down and get a rough understanding about whats going on in the lab. Having an understanding and being able to contribute maybe a comment or two in group meeting will go a long ways towards establishing trust (must be ligit contributions, nothing will sink your ship faster than stupid comments).

5). Be seen but not heard. Its best to just absorb whats going on around you when you start in a lab. (Once again it all goes back to the trust between you and the grad students or PI). Generally undergrads will not have much to add if they are just starting in a lab. Get a feel for what is expected, then start to add to conversations. Once again Don't Be a Dick, grad students (in general) hate undergrads and being a dick will only further cement that hatred.

6). Work your butt off. Plain and simple, if you show up early in the morning and work late then you will gain respect.

7). Always have something to do. Don't sit around and read ESPN or SDN while in lab, that looks really bad. Either be working on your project, find something to clean, or be reading scientific articles that are relevant.

8). If you really want to get published find a specific area that your group is working on that you can specialize in. For example, if your group has to learn how to do a specific assay and no one is really sure how to do it (or if there is something that is going wrong and no one knows why), then you take initiative and try to learn how to do the assay (or whats going wrong) by reading journals, talking to other groups. If you show initiative, then the people in your group will trust you with more and more things.

9). Just as Rome wasn't built in a day, so to you will not become king of the lab (to borrow a term from "Bones") over night. It takes time, but each day inch closer and closer to your goal by building trust and showing responsibilities.

10). Focus on what has been given. I ran across an article (maybe it was here on SDN or elsewhere) but it said that often those who want more responsibility in life often are not taking care of the things that they are responsible for. An example that I have seen: an undergrad wanted more responsibility and he was confused why he wasn't able to get more work (more involved) in lab. Well ends up that the guy had been asked to order paper for the printer (pretty petty task), well he never did and after a week of having no paper the grad students ordered it themselves, needless to say he was not given more responsibilities.

11). Don't kiss ass. There is nothing that grad students hate more than an undergrad kissing the PI's ass and going over their heads. Judge how the grad students interact with the PI and go from there. Some groups go get beers with their PI; in other groups, the PI will be in lab 15 minutes a week and thats all the contact that they have with the grad students. Just use judgement on when to go to the PI, sometimes its necessary or beneficial, but not normally.

12). Know what you are doing. The final thing I will say about gaining trust is know why you are doing something. If you are using a mass spec machine, you should probably know why you are using it, if or what kind of separation you are using and why. Example: I was shadowing a friend in her lab and I was asking her some questions about what she was doing and why she was using this chemical as opposed to another (I was trying to learn the technique not throw her under the bus) and she had no idea on any of these simple "science" questions, and her PI was standing right there and had a look of horror on his face. So simply, don't horrify your PI by not knowing what you are doing.

12*). Just a note, even if you are not getting paid for your work that does not mean that you are not costing the lab money. Because depending on what materials you are using, you can be really blowing through money just in materials and so if you screw up you could potentially lose the lab thousands of dollars.

13). How do you find a good lab (I come full circle). A great way is to ask a trusted elderly science professor. Typically (and I say typically realizing that this is not the case always) elderly professors will not be as heavily involved in their own research but they will have an ear to the ground as to what is going on in each lab. If you know this elderly professor well (or any professor) you should go to them and ask them, who is doing good research and where could I get significant research experience.

13*). (I know that I will get no award for brevity, so I will continue in my thesis). Research experience >>> first authorship. Now let me explain this. If you are looking towards getting into medical school or MSTP or MD/PhD then you might (if MD/PhD then you will) be asked about your research. Now if you say, "I was first author" (or 2nd or 4th or whatever) and they ask, "Oh could you explain your project and how you contributed?" And if you respond with "oh, well I mainly did grunt work, but I was Nth author, look." Then you are toast. Its much better to go into those interviews being able to say, I was given these responsibilities (actual research experience) but I not fortunate enough to get a publication, then the interviewers will look much more favorable upon this. You can get publications and be in lab 3 hrs/ week while others can be working 30 hrs/week and never get a pub. (Life isn't fair, this is why everyone says its luck because it is) And whats even more important than just know techniques (because even monkeys can learn techniques) is learning what questions need to be asked and how one goes about answering those questions <----- most important thing to learn in research.

I think I'm on 14). Now here is something I am unsure about so take this with a grain of salt. (Any comments would be gladly accepted on this issue). There will be lab drama. There always is. Grad student X hates undergrad Y and threatens to kick him out. Or PostDoc Z gets on everyones' nerves and Grad Student J calls them out on it. Whatever the case, it will happen. Its best to be as neutral as possible in whatever situation, but of course thats not always possible. DONT PLAY BOTH SIDES, this will bite you in the ass because "grad students always talk" and you will be found out. So keep your head down when possible.

14*). Also related to this, is the blame game. Things go wrong and PI or PostDocs or Grad students have to blame someone. The last thing that you should do is point figures (its just not professional). If your PI comes to you and is telling you that you completely screwed up the experiment because some concentration was wrong (even though it was the other undergrad) sit there and take it and then afterwards go and talk with the other undergrad. (Sounds stupid, but the PI will trust you more because you were willing to be corrected and as long as you are humble and promise to do it right next time then he will trust you more; also the other undergrad will be thankful to you for not ratting him out and others in your lab will see what happened and the will know whose fault it really is and things will trickle up (maybe not specifically that situation but character traits) to the PI)).

(I've noticed that these paragraphs keep getting longer and I use too many parenthesis) (Also by the time that I finish this post, this thread will be on the 3rd page) But I'm on a roll so I will continue <most of the bad things that have happened have happened to me, so I'm trying to share my knowledge so that others don't have to go through these thing> Also I'm still in the general area of telling how to get publications.

15). Rule 1 for when you are looking at a new lab to perhaps join. If all the grad students are foreign then there is a chance that the PI works the students awfully hard. (Not so sure how true this is but this is what I have been told by my grad students and others). So investigate a little if everyone is foreign to makes sure you are not getting into an environment that might not be the best for you.

16). Now I've talked quite a bit about labs where there are grad students and post docs, but there are labs where there are no grad students just the PI and undergrads. Now these labs can go two ways: 1) The PI is heavily involved or 2) the PI is not involved. I will speak to the first and comment on the second later. When the PI is heavily involved this can be very good and a great learning experience. The PI will take time to teach you protocol and techniques and if you show interest your responsibility can increase. This is an excellent place to learn about "What question ought to be asked and how to answer those questions" because you can ask the PI, why are we doing this or what made you choose this chemical instead of that chemical. [Just a note on these labs, you need to be careful that the PI is not simply using the undergrads for sheer grunt work. I have seen several who only have undergrads do mindless, repetitive work which is great but learning is not taking place].

Keys to striving in these labs are hard work and following the instructions of the PI to the letter. Since the PI is the only one above you, it is key to gain his trust.

Now as to labs where the PI is hands off without grad students. These are tricky labs. They can be great, they can be horrible. These labs will generally have an upperclassman who "oversees" the lab. (I have no idea how many of these actually exist but this probably applies to all hands-off labs) These labs are really tough to screw up but also really tough to accomplish much in. In general I think these are excellent labs to learn how to "think for yourself" in. But these are labs where you can display leadership (and once you are the "overseer," dealing with everyone's problems). Generally these labs will not turn out the most research papers but these can be excellent places to gain experience.


Now since I love rankings I will put some rankings out (note these are just from my experiences which is limited to one school and the stories that I have read here on SDN) (*These are only meant as a rough guide, to truly understand a lab, nothing replaces your own background checks).

Most likely to be producing papers:

1. Young teachers (on tenure track) w/ grad students
T2. Tenured teachers w/ grad students
T2. Teachers (on tenure track) w/o grad student but PI is involved
4. Teachers (not on tenure track) w/o grad students but PI in involved
5. Teachers (not on tenure track) w/o grad students and PI is NOT involved

Mostly likely for student to be ignored:

1. Tenured teachers w/ grad students
2. Teachers (not on tenure track) w/o grad students and PI is NOT involved
3. Young teachers (on tenure track) w/ grad students
4. Teachers (not on tenure track) w/o grad student but PI is involved
5. Teachers (on tenure track) w/o grad students but PI in involved

Most room for "aggressive expansion" (to quote the joker):

1. Young teachers (on tenure track) w/ grad students
2. Teachers (on tenure track) w/o grad students but PI in involved
3. Teachers (not on tenure track) w/o grad students and PI is NOT involved
4. Teachers (not on tenure track) w/o grad student but PI is involved
5. Tenured teachers w/ grad students

Best Environment for a Go Getter, A self Motivated person (these people will feel stifled by grad students or PIs watching over their shoulder):

1. Young teachers (on tenure track) w/ grad students
2. Teachers (not on tenure track) w/o grad students and PI is NOT involved
3. Teachers (on tenure track) w/o grad students but PI in involved
4. Teachers (not on tenure track) w/o grad student but PI is involved
5. Tenured teachers w/ grad students

Best Environment for Students who like step by step instructions and are very by the book (there is nothing wrong with these people they will make great doctors) (they will feel completely lost and will become ignored in large labs where they might be tossed to the wind):

1. Teachers (on tenure track) w/o grad students but PI in involved
2. Teachers (not on tenure track) w/o grad student but PI is involved
3. Tenured teachers w/ grad students
4. Young teachers (on tenure track) w/ grad students
5. Teachers (not on tenure track) w/o grad students and PI is NOT involved <Stay away from this lab, you will drown>

Closing words of advice:

Don't feel bad sometimes it is best to move on from one lab to another.

Finding out which type of lab will help you be the best that you can be which will lead to publications or significant research experience or both!

Make sure that the lab can have side projects. If the lab only uses one machine and the machine is always being used, then you could sit and do nothing. (I had a friend who had this happened to him, he had fun sitting doing nothing 40hrs/week all summer).

If you dont like the subject then you wont like the research and you wont work hard and you wont get published. Start with what you like and work from there (I understand small schools and this is not always possible but PIs at smaller schools are a little bit more willing to work with you so that you are interested in the research)

Oh, the first week always sucks. Just gut through it, it will get better.

Bench research is not for everyone, you dont have to love it. You can go to your med school interview and they ask you about your research and if you explain it and then volunteer the information that you did not enjoy it, the interviewer will not look down on you for this but will respect your life decision because bench research is not for everyone. But with this being said, bench research is only one type of research and if you hate bench research then you won't necessarily hate all research. So its ok to close the door to bench research but don't be naive and close the door to all research.

Well, I should end my treaties here. I apologize for my brevity (PM me if you would like me to expand on any subject, I don't want to burden this wall anymore). (The brevity thing above is a joke). Finally, I once again state that these are simply my observations and should be taken as observation and helpful words of advice not as set in stone law. I myself have worked in a lab with a young PI (on tenure track) with grad students and in a lab of a tenured PI w/o grad students and he was not involved. I have shadowed quite a few labs and seen how other labs work, but do not claim all knowledge in those other labs. Also, every lab, every university is different and these rules could be completely null in some places, but I doubt that hard work and politeness will fail you. I myself have 3 first author papers and am working on more (I saw this not to brag but to simply give credence to what I saw). However, I have only finished two years of undergrad and thus anything about medical school is what I have been told by trusted sources who could be wrong but I have only tried to pass on credible information. I hope that this is helpful to anyone who is interest and I apologize for any typo's its 3 a.m. at this point in time.

Wow 7 pages in Microsoft word (I have said too much!)
 
And you should be very proud of that journal's <1.0 impact factor.

Edited to add:
Although, really this isn't something undergrads should worry about. But your utter lack of a helpful contribution brings out the snarkiness in me.

According to one ranking service, JCTS is the second worst journal in all of cardiac research, right below something called "Netherlands Heart Journal" and above the "Hellenic Journal of Cardiology". I actually don't know what the Hellenic Journal of Cardiology is. Incidentally, July 2011 was the first month that HJC was even awarded an impact factor, so your stay as only the second worst journal in the entire field may soon come to an end. Serious question: Is JCTS even peer reviewed? It is, of course, but I did not think it was even possible to publish like this in the United States. There is probably a good reason your PI is letting you take first author on this one...

haha wow you guys are douche bags, and so is the guy boosting about his journal articles though
 
Once again Don't Be a Dick, grad students (in general) hate undergrads and being a dick will only further cement that hatred.

There was a lot of good information in that wall of text, but this is one thing that drives me nuts. Graduate students do not hate undergrads. Graduate students dislike people who waste their time. I can't really think of anyone who does. That's not referring to people who are new to the lab environment but people who are in the lab in order only to fill a cookie cutter requirement and show no interest in the work being done or in the quality of the work they produce. If you're truly interested in doing research, in learning and producing quality work, then you'll have absolutely no problems working in a lab... with graduate students or anyone else.
 
Great advice Fishin316, I'm buzzing with ideas now.:bow:
 
There was a lot of good information in that wall of text, but this is one thing that drives me nuts. Graduate students do not hate undergrads. Graduate students dislike people who waste their time. I can't really think of anyone who does. That's not referring to people who are new to the lab environment but people who are in the lab in order only to fill a cookie cutter requirement and show no interest in the work being done or in the quality of the work they produce. If you're truly interested in doing research, in learning and producing quality work, then you'll have absolutely no problems working in a lab... with graduate students or anyone else.

Your right, I probably phrased that wrong. Most grad students dislike the idea of undergrads. Generally they have just had bad experiences with undergrads who waste their time, but it is possible to have a good working relationship or even to be friends with the grad students (but you only get to that point by building trust). So yes, working with grad students is not difficult but people who are heading into labs need to know that grad students are generally jaded towards undergrads because the previous ones have just wasted time.

Thanks for pointing that out whatageek.
 
I think if you want to come across as an intelligent researcher and be treated as such, you need a genuine interest in research and the topic. If you're only interested in getting a publication to throw on your application, it comes across as really immature and tacky. Don't strive so much to put notches on your belt - find something that you're actually interested in and curious about, talk to your PI, and tell him / her that you want a chance to do some original work. If you don't have any scientific curiosity or drive to do independent work, I'd probably question what your interest in medicine is.
 
Your right, I probably phrased that wrong. Most grad students dislike the idea of undergrads. Generally they have just had bad experiences with undergrads who waste their time, but it is possible to have a good working relationship or even to be friends with the grad students (but you only get to that point by building trust). So yes, working with grad students is not difficult but people who are heading into labs need to know that grad students are generally jaded towards undergrads because the previous ones have just wasted time.

Thanks for pointing that out whatageek.

While in grad school, I mentored a lot of pre-med undergrads who were just there to put research on their applications and get an LOR - many didn't care about the research and were just going through the motions. It takes a lot of time and effort to mentor students, so it bothered me that I was spending time I could've been doing research to help someone who didn't care. I have had some undergrads who really care though, and if they're interested, I will go above and beyond to help them.
 
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