D datdat Full Member 10+ Year Member Joined Jul 5, 2009 Messages 221 Reaction score 0 Points 0 Pre-Dental Aug 30, 2009 #1 Advertisement - Members don't see this ad I'm just wondering why protic solvent is not good for Sn2 rxn.. could anybody tell me the reason/ ?
Advertisement - Members don't see this ad I'm just wondering why protic solvent is not good for Sn2 rxn.. could anybody tell me the reason/ ?
V vinny13 New Member 10+ Year Member Joined Jul 23, 2009 Messages 1 Reaction score 0 Points 0 Pre-Dental Aug 30, 2009 #2 datdat said: I'm just wondering why protic solvent is not good for Sn2 rxn.. could anybody tell me the reason/ ? Click to expand... Polar protic solvent is not used in SN2 because it will stabilize the nucleophile and slow down the reaction. For SN1 a carbocation intermediate is formed and a polar protic solvent is needed to stabilize the carbocation. Upvote 0 Downvote
datdat said: I'm just wondering why protic solvent is not good for Sn2 rxn.. could anybody tell me the reason/ ? Click to expand... Polar protic solvent is not used in SN2 because it will stabilize the nucleophile and slow down the reaction. For SN1 a carbocation intermediate is formed and a polar protic solvent is needed to stabilize the carbocation.
