Do you mean, online pre-reqs? I'm taking 2 online classes now and did one a couple summers ago, and the schools I contacted said it wouldn't be a huge deal. But, they're for my major and not pre-reqs. (I'm a health science major.) I also asked them a long time ago if taking summer classes was looked down on (I did physics last summer) and they said it wasn't a problem either. But, for pre-reqs, I'm not really sure. I know the CC where I live offers online biology, and I'm not really sure how that happens with a lab.