RNA splicing...

[Temperature101]

Eukaryotic DNA is initially transcribed as hnRNA, then spliced to form mature mRNA. Which of the following is true of RNA splicing?
A. Introns remain in the mature mRNA.
B. Splicing of hnRNA from a single gene can be variable
C. Splicing of hnRNA occurs in the cytosol.
D. Exons are excluded from the mature mRNA.
This is an easy question but I think they provide two correct answers.

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[red doctober]

Eukaryotic DNA is initially transcribed as hnRNA, then spliced to form mature mRNA. Which of the following is true of RNA splicing?
A. Introns remain in the mature mRNA.
B. Splicing of hnRNA from a single gene can be variable
C. Splicing of hnRNA occurs in the cytosol.
D. Exons are excluded from the mature mRNA.
This is an easy question but I think they provide two correct answers.

A. Wrong. Exons remain in the mature mRNA. Easy way to remember is that exons exit the nucleus.
B. YES. Look up "alternative splicing."
C. Wrong. This happens in the nucleus.
D. Wrong. Introns are excluded from the mature mRNA.

So you can immediately throw out A and D because they are saying the same thing but in different words...

 

[Morsetlis]

Eukaryotic DNA is initially transcribed as hnRNA, then spliced to form mature mRNA. Which of the following is true of RNA splicing?
A. Introns remain in the mature mRNA.
B. Splicing of hnRNA from a single gene can be variable
C. Splicing of hnRNA occurs in the cytosol.
D. Exons are excluded from the mature mRNA.
This is an easy question but I think they provide two correct answers.

The intragenic regions (introns) are spliced out of the hnRNA, and the expressed regions (exons) are left in the mRNA. Splicing occurs in the nucleus, and splicing of hnRNA can be variable, as evident in alternative splicing of the IgM transcript into IgD in mature naiive B cells.

 

[Temperature101]

A. Wrong. Exons remain in the mature mRNA. Easy way to remember is that exons exit the nucleus.
B. YES. Look up "alternative splicing."
C. Wrong. This happens in the nucleus.
D. Wrong. Introns are excluded from the mature mRNA.

So you can immediately throw out A and D because they are saying the same thing but in different words...

Oh sh..t...I thought I was reading nucleus instead of cytosol..I miss a lot of questions like that. I know about alternative splicing.Thanks

 

[Temperature101]

I would hate myself If I miss an easy question like that on the real stuff because I fail to readd the question properly.