The first cardinal decision-making guideline in the DSM-5 diagnosis of schizoaffective disorder, according to the DSM-5 workgroup, is that
when psychotic symptoms occur during a mood episode of depression, mania, hypomania, or mixed episode, the DSM-5 indicates that the diagnosis must be either
psychotic depression or psychotic
bipolar disorder.
[2] Only when a psychotic condition lasts two-weeks continuously or longer without mood symptoms, is the diagnosis either schizophrenia or schizoaffective disorder.
[2]
The second cardinal guideline in the DSM-5 diagnosis of schizoaffective disorder is one of timeframe.
DSM-5 requires two episodes of psychosis (whereas DSM-IV needed only one) to qualify for the schizoaffective disorder diagnosis.
[2] As such, it is no longer an "episode diagnosis."
[2] The new schizoaffective framework looks at the time from "the [first episode of] psychosis up to the current episode [of psychosis], rather than only defining a single episode with [co-occurring] psychotic and mood
syndromes."
[2] Specifically, one of the episodes of psychosis must last a minimum of two weeks without mood disorder symptoms, but the person may be mildly to moderately depressed while psychotic.
[2] The other period of psychosis "requires the overlap of mood [disorder] symptoms with psychotic symptoms to be conspicuous" and last for a greater portion of the disorder