Honestly it depends on how you learn best and how much money you're willing to spend. Self-study is usually cheaper, but works best if you are highly motivated as an individual. If you're like me and very unmotivated to study without outside pressure, tutoring or a class might be better for you.
(The rest of this is all personal experience and contains some elements of "do as I say, not as I do.")
I chose to self-study and spent about $40 on a Kaplan PCAT prep book. I opened it once the day I got it, read about 5 pages about the format of the exam, and didn't open it again until three days before my exam. At that point I spent every minute outside of work cramming, focusing mostly on organic chemistry and the writing section. I got a 97th percentile on the exam, but I was very stressed and did not expect to do any better than ~70. Do not self-study if you know that you will not have the self-motivation necessary.