Sn1,2 / E1,2

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SN1:
- Polar protic solvent
- Bulky nucleophiles
- Weak bases

E1:
- Same as SN1, but preffered at higher temperatures

SN2:
- Polar aprotic solvent
- Less substitution
- Weaker base than E2

E2:
- Strong base (strong enough to remove a H)


anything else?

 

[andyjl]

ive got a question regarding the E1 and E2. So on something like this reaction

2-chlorobutane 1. (CH3)3CO-Na+ 2. (CH3)3COH would give you 1-butene.

the base is bulky and is a secondary halide which would make it good for E2, but for E2, you need a polar Aprotic solvent, in this case we have a tertiary alcohol as the solvent, which is polar protic...can someone explain this discrepency??

I've been noticing this a lot

 

[Anemone]

if you google this, you'll find really good/clear charts that list all the differences right next to each other. additionally, its in the back of the destroyer orgo in the solution section somewhere.

 

[levyusupov]

get the DAT destreyer and there is a full review of these important mechanisms. the info covered will help you to aswer ur qustion and other orgo questions. get it and you wan't regret it, promise.

 

[TimeforDAT]

if you google this, you'll find really good/clear charts that list all the differences right next to each other. additionally, its in the back of the destroyer orgo in the solution section somewhere.

i have seen this too in the destroyer