Someone clarify for me: Error in Destroyer Biology

[jasminetea7]

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Hello,

I apologize in advance if someone had asked this question already.

#26 of Biology section (2010 version) asks which hormone activates adenylyl cyclase?

Choices given:
a) Trypsin
b) Glucagon
c) Epinephrine
d) FSH
e) LH

Now my understanding was that only the peptide hormones activate adenylyl cyclase when they bind to the membrane receptor. According to the solution, the answer is c) Epinephrine. But isn't b) Glucagon also a peptide hormone? And when I looked up Wikipedia, FSH and LH were also peptide hormones.
Was I wrong about the peptide hormones activating AC? 😵
Or do you think this is a mistake?

 

[oae]

For the DAT exam, you often have to pick the BEST answer. So it can get tricky if you read into things.

For the above choices, when I see trypsin I think protein breakdown, when I see glucagon I think blood glucose increase, when I think FSH and LH I think ovarial processes. All of these hormones are often very specifically related to very specific functions (none of which ever mentioned adenyl cyclase in any Bio book I read)

However, when I think epinephrine, no specific funtion comes to mind since its effects are so widely ranged. Epinephrine just seems like such broadly importanly molecule so its the safest choice.

This just my opinion. So remember. Pick the best answer.

 

[dentalWorks]

My opinion here is that this type of question format will never appear on the real DAT for the following reasons: 1) the answer choice doesn't have "more than 1 of the above", 2) it requires a GREAT deal of biochemistry knowledge of how cells physiologically respond to EACH of those molecules, and 3) its not what I like to call "general biology knowledge", you see most of the questions from the biology are testing your ability to apply "basic biology knowledge" to solve/answer the questions.

By the way, adenylyl cyclase, from what I remember, is a process that involves the production of cAMP (especially useful for 2nd-ary messengers). Of the top of my head adrenalin (epinephrin) is one of the molecules that attached on the cell surface to initiate this 2nd-ary cAMP response.... and IN ONE PARTICULAR situation, liver cells CAN use this adenylyl cyclase process when glucagon attaches to receptor, this eventually leads to the overproduction of glucose to being rushed into the bloodstream.

So, answer should be adrenalin and glucagon

 

[i4everpaki]

i actually took my cell bio test today, and a similar question was on it. it is epinephrine/adrenaline. like DentalWorks said it is involved in the process of 2nd messengers. Its a tough question if you do not have knowledge of cell-biology, hope questions these detailed are not on the DAT.

 

[UCSD6]

Your right Jasmietea it's both. I dont think its that hard of a question though and is fair game for the DAT, couse both adrenaline and glucagon are well studied hormones and involve the well know pathway of G protein couple receptors --> G protein --> Andyly Cyclase --> cAMP --> some effector if I remember correctly.