Yep! And no... They'll wait on reviewing your app because you don't meet their requirements. I e-submitted without two LORs, actually... a chemistry professor and a dentist. After you e-submit you have more time to upload the LORs anyway because they have to verify your GPA. Even if your transcripts are already "in"/processed, you have 2 weeks-ish to upload them. Even if you don't upload them "in time", schools will wait on you. Most (or all, maybe?) will send you an email that says "your application is missing X and Y".