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Ha I was actually joking around since someone mentioned 50 shades and that was a Twilight fan fic, and so is 13 reasons why. But to answer the question, Twilight probably hasn't, but 13 did increase awareness and discussion about suicide and mental health. For changing practices, do you mean medical practices? If you do then I have no idea.
I'm not talking about medical practice; I wouldn't expect a pre-med to have any ideas in that regard. Has 13 reasons changed attitudes and practices regarding suicide and suicide prevention aimed at teens? We know that when Netflix show by the same name dropped that there was an uptick in teen suicides. Has there been any reaction by universities, high schools, and organizations serving teens to have conversations about these books?
Has Twilight brought up discussions of sexuality among teens? (I haven't read any of that series so I'm somewhat unclear on it aside from the fact that involves vampires.)