Thyroid and parathyroid don't have opposing effects. Thyroid hormone (t3 & t4) regulate metabolism. They are controlled by tsh released from the pituitary and they are created in the thyroid. Parathyroid is made by parathyrpid glands. Parathyroid takes calcium from bones to increase the concentration in the blood. Calcitonin does the opposite, adding calcium back to the bones.