I actually transferred medical schools during the summer after my second year. I thought it was going to be horribly difficult but it actually was really easy for me. My roommate was the first person who suggested transferring. She got married right before starting medical school to a man in Oklahoma and we were in California and wanted to move back to Oklahoma to be with him. Unfortunately there were no spots at that medical school and so they put her on a "waiting list" which basically meant there was no way she was going to get there. I, on the other hand, sent my application into a school on the east coast where my boyfriend was living and had no problems. I basically copied my med school application, asked my undergrad institution to forward all of my letters of recommendation from when I applied prior to first year (which thankfully they still happened to have) to the school, sent them my transcripts and a letter from my dean giving them my rank and saying that I was in good standing. They invited me to interview, which was a 10 minute conversation with the dean, after which I was told I was welcome to join them. Now, I need to specify that my particular graduating class at the school I transferred into had lost around 20 members over the course of the first two years and had not gained a single person. The public medical school was more than happy to accept my out-of-state tuition too. So, my conclusion is that if you find a school that has a slot (i.e has had a lot of drop-outs/failures/repeating students), has a financial reason to accept an additional student, and your grades are average or above average at your current medical school, and you have a good reason to move (i.e fiance, husband, sick family member) then it should work out.