Do you follow any cut-offs for s. creatinine while doing CT scans with IV contrast to r/o trauma related solid organ injury or aortic injury?
just out of pure nerdy curiosity (spare me the "you've got plenty of time before you worry about this" speech), can someone briefly explain the clinical importance of creatinine levels in a trauma ct?
Contrast can be nephrotoxic (because of the same reason that it shows up opaque on radiographic studies - it's dense), and, if the renal function isn't optimal, the contrast bolus can cause renal failure. When I was a resident, the cards guys would encounter this - patient needed a cath, but renal function was poor, and they know that the cath would be the last hurrah for the patient's kidney (and dialysis thereafter), but they needed cath.
In your average trauma victim, the age is generally younger than your polymorbid medical patient. The possibility of poor kidney function is there, but MUCH less likely than in the other group of patients.
Correct me if I'm wrong, but it is my understanding (I admittedly haven't done all that much reading on this subject) that the creatinine bump after a contrast bolus is temporary and it is rare for it to cause anything more than a short-term AKI.
That clears it up. Never really thought about the possible toxicity from giving contrast of all things to someone with failing kidneys...again, just my lowly medic's interpretation, but won't a fudged up aorta or hemo/pneumo kill you way quicker than renal failure induced by contrast? I'd scan now and ask chem levels later looking at things from a layman's point of view.
When it comes to a sick trauma patient and the contrast/Cr issue I feel it's better to beg for forgiveness than to ask for permission, so I scan them before the labs are back.
Now, on the patient who is not sick and who has a low pretest probability of traumatic injury and a high PTP for renal insufficiency I'll check a Cr and hydrate while waiting for results. I hydrate for 2 reasons: 1) Often times the Cr will come down to below the "cut-off" with a little IVF and 2) The most important factor in preventing contrast induced nephropathy is ensuring adequate hydration prior to contrast administration.
That clears it up. Never really thought about the possible toxicity from giving contrast of all things to someone with failing kidneys...again, just my lowly medic's interpretation, but won't a fudged up aorta or hemo/pneumo kill you way quicker than renal failure induced by contrast? I'd scan now and ask chem levels later looking at things from a layman's point of view.
unfortunately in the case of trauma I have had to argue w/ CT that there is no reason to wait for a chem 7 in a young healthy patient to obtain a CT in a patient that could be emergent.
snip...which lands them on disability and raises their 10 year mortality significantly.../snip
I now have the luxury of having point-of-care (I-STAT) testing where I work. It takes only 5 minutes to get a chem-8 (10 for a troponin and BNP). It's hard to defend oneself against nephrotoxicity even in a young person if you have access to POC testing. It really doesn't hold up things very much to do a POC chem-8 prior to CT.