typo??

[de297]

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hey guys
theres this card in pathology decks in the neoplasia section that says most likely indication that the neoplasm is malignant in following microscopic findings(well i reframed the q to make it short,but this is what it means)
pleomorphism
atypia
metastasis
increased nuclear/cytoplasmic ratio
necrosis
answer is metastasis.
but how on earth can metastasis be a microscopic finding?i would go with increased nuclear/cytoplasmic ratio.
what do u think??

 

[de297]

another one
among the lung cancers decks say its scc thats most common 35%, but USMLE says its adenocarcinoma at 35% and scc at 25% followed by small cell at 25%.
any ideas??

 

[porcelain258]

u r right but if the q didnt mention about microscopic findings ,then of course the ans would be metastasis

 

[porcelain258]

most common lung cancer is SCC .....so decks shd be right

 

[Sinatra Frank]

most common lung cancer is SCC .....so decks shd be right

most common cancer is adenocarcinoma,,both kaplan (nbde and usmle say so) and i would take them as the best resourse.

first question is asked in a wrong way IMO..
I stoped taking the decks as 1 source..if u have doubts check the kaplan or internet..

 

[generationX]

hey guys
theres this card in pathology decks in the neoplasia section that says most likely indication that the neoplasm is malignant in following microscopic findings(well i reframed the q to make it short,but this is what it means)
pleomorphism
atypia
metastasis
increased nuclear/cytoplasmic ratio
necrosis
answer is metastasis.
but how on earth can metastasis be a microscopic finding?i would go with increased nuclear/cytoplasmic ratio.
what do u think??

could you write the question without rephrasing it?

 

[njsmahal]

most common cancer is adenocarcinoma,,both kaplan (nbde and usmle say so) and i would take them as the best resourse.

first question is asked in a wrong way IMO..
I stoped taking the decks as 1 source..if u have doubts check the kaplan or internet..

SCC used to be the most common in the early 20th century but now its adenocarcinoma thats the most common. and this was found to be the trend 1985 onwards or something like that. i think you got the answer as SCC from the released papers of 1975 -1985

 

[njsmahal]

hey guys
theres this card in pathology decks in the neoplasia section that says most likely indication that the neoplasm is malignant in following microscopic findings(well i reframed the q to make it short,but this is what it means)
pleomorphism
atypia
metastasis
increased nuclear/cytoplasmic ratio
necrosis
answer is metastasis.
but how on earth can metastasis be a microscopic finding?i would go with increased nuclear/cytoplasmic ratio.
what do u think??

increased nucleocytoplasmic ration doesnt tell whether it is malignant or benign. it just tells that there is a cnacer cell that has developed to determine its malignancy we see the level of differentiation and metastasis. so necrosis,pleomorphism, nucleocytoplasmic ratio are gone. atypia is just an abnormality in the cell which can be linked with infections as well. so i guess all we are left with is metastasis which is the right choice for this and is a marker for determining malignancy

 

[iris999]

very nice explanation njsmahal... keep it up

 

[iris999]

very nice explanation njsmahal... keep it up

but the question is to find microscopic feature ... dont u think metastasis is not a microscopic feature....... can u clarify ....

 

[iris999]

most common cancer is adenocarcinoma,,both kaplan (nbde and usmle say so) and i would take them as the best resourse.

first question is asked in a wrong way IMO..
I stoped taking the decks as 1 source..if u have doubts check the kaplan or internet..

why u decided that decks are not the first source of information.. i'm worried because i'm depending on decks for my preparation... not yet started reading kaplan review...😕

 

[Sinatra Frank]

why u decided that decks are not the first source of information.. i'm worried because i'm depending on decks for my preparation... not yet started reading kaplan review...😕

i meant that i decided that will be best for me is to read the kaplan first and then ill read the decks.. i think kapkan brings more information and the decks only focus on the "have to know topics"..
dont get me wrong. i think (and many people who scored 90+) that decks are must.. i just dont use them as 1st source but as repetition ( in 4 weeks ill know if i was right 🙂

and by the way..when the tumor has penetrated the basement membrane.. u can call it malignant and can assume metastasis or local invasion. this is the hallmrk difference bw benign and malignant tumor..

 

[Behnam Nazem]

I also think the same...the answer is metastasis...because all the other choices are cytological atypia that can occur also in Carcinoma in situ...all these cytological atypias can occur in malignant tumor....but the main difference btw benign and malignant tumor is local invasion and metastasis....benign one does NOT metastasize...

 

[njsmahal]

I also think the same...the answer is metastasis...because all the other choices are cytological atypia that can occur also in Carcinoma in situ...all these cytological atypias can occur in malignant tumor....but the main difference btw benign and malignant tumor is local invasion and metastasis....benign one does NOT metastasize...

metastatsis is not a gross feature .... we cannot find out whether the tissue is from the same organ or metastasised until we do a microscopic exam of it. otherwise grossly a cancer of the colon can be just its own but if we do a microscopic exam we can determine stratified squamous cells in it suggesting it metastasised from esophagus.... thats what i think