I guess "acutally produce" is also kind of misleading -- U of C EM strength seems to be in basic science research. Sure it may not be represented as much in the EM circles, but if you look in JAMA, Circulation, AHA meetings, Resuscitation, etc. -- they are pretty well represented in those forums. Here is just a sample of a a pubmed search for "Vanden Hoek" -- one of the research faculty at U of C. Considering that there is federal grant funding behind the research is impressive. I defintely think that U of C is probably the only place in Chicago where this type of basic science EM research is being done. The question that I have is that should this make a difference with regard to residency training? Perhaps if a resident wants to get involved in basic science research, but knowing the characteristics of most EM folks -- I don't think this will be much of a factor.
The flight program may be a bigger factor as it directly impacts the residency training.
1. Abella BS, Alvarado JP, Myklebust H, et al. Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA 2005; 293, 305-310.
2. Abella BS, Rhee JW, Huang KN, Vanden Hoek TL, Becker LB. Induced hypothermia is underused after resuscitation from cardiac arrest: a current practice survey. Resuscitation 2005; 64, 181-186.
3. Abella BS, Sandbo N, Vassilatos P, et al. Chest compression rates during cardiopulmonary resuscitation are suboptimal: a prospective study during in-hospital cardiac arrest. Circulation 2005; 111, 428-434.
4. Idris AH, Roberts LJn, Caruso L, et al. Oxidant injury occurs rapidly after cardiac arrest, cardiopulmonary resuscitation, and reperfusion. Crit Care Med 2005; 33, 2043-2048.
5. Qin Y, Vanden Hoek TL, Wojcik K, et al. Caspase-dependent cytochrome c release and cell death in chick cardiomyocytes after simulated ischemia-reperfusion. Am J Physiol Heart Circ Physiol 2004; 286, H2280-6.
6. Abella BS, Zhao D, Alvarado J, Hamann K, Vanden Hoek TL, Becker LB. Intra-arrest cooling improves outcomes in a murine cardiac arrest model. Circulation 2004; 109, 2786-2791.
7. Shao ZH, Vanden Hoek TL, Li CQ, et al. Synergistic effect of Scutellaria baicalensis and grape seed proanthocyanidins on scavenging reactive oxygen species in vitro. Am J Chin Med 2004; 32, 89-95.
8. Shao ZH, Xie JT, Vanden Hoek TL, et al. Antioxidant effects of American ginseng berry extract in cardiomyocytes exposed to acute oxidant stress. Biochim Biophys Acta 2004; 1670, 165-171.
9. Vanden Hoek TL, Kasza KE, Beiser DG, et al. Induced hypothermia by central venous infusion: saline ice slurry versus chilled saline. Crit Care Med 2004; 32, S425-31.
10. Shao ZH, Becker LB, Vanden Hoek TL, et al. Grape seed proanthocyanidin extract attenuates oxidant injury in cardiomyocytes. Pharmacol Res 2003; 47, 463-469.
11. Shao ZH, Vanden Hoek TL, Xie J, et al. Grape seed proanthocyanidins induce pro-oxidant toxicity in cardiomyocytes. Cardiovasc Toxicol 2003; 3, 331-339.
12. Vanden Hoek TL, Qin Y, Wojcik K, et al. Reperfusion, not simulated ischemia, initiates intrinsic apoptosis injury in chick cardiomyocytes. Am J Physiol Heart Circ Physiol 2003; 284, H141-50.
13. Anderson T, Vanden Hoek TL. Preconditioning and the oxidants of sudden death. Curr Opin Crit Care 2003; 9, 194-198.
14. Wischmeyer PE, Vanden Hoek TL, Li C, et al. Glutamine preserves cardiomyocyte viability and enhances recovery of contractile function after ischemia-reperfusion injury. JPEN J Parenter Enteral Nutr 2003; 27, 116-122.
15. Lebuffe G, Schumacker PT, Shao ZH, Anderson T, Iwase H, Vanden Hoek TL. ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel. Am J Physiol Heart Circ Physiol 2003; 284, H299-308.
16. Levraut J, Iwase H, Shao ZH, Vanden Hoek TL, Schumacker PT. Cell death during ischemia: relationship to mitochondrial depolarization and ROS generation. Am J Physiol Heart Circ Physiol 2003; 284, H549-58.
17. Nolan JP, Morley PT, Vanden Hoek TL, et al. Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation. Circulation 2003; 108, 118-121.
18. Shao ZH, Vanden Hoek TL, Qin Y, et al. Baicalein attenuates oxidant stress in cardiomyocytes. Am J Physiol Heart Circ Physiol 2002; 282, H999-H1006.
19. Vanden Hoek TL. Preconditioning and postresuscitation injury. Crit Care Med 2002; 30, S172-5.
20. Shao Z, Li C, Becker LB, et al. Qian-Kun-Nin, a Chinese herbal medicine formulation, attenuates mitochondrial oxidant stress in cardiomyocytes. J Ethnopharmacol 2001; 74, 63-68.
21. Xu Z, Cohen MV, Downey JM, Vanden Hoek TL, Yao Z. Attenuation of oxidant stress during reoxygenation by AMP 579 in cardiomyocytes. Am J Physiol Heart Circ Physiol 2001; 281, H2585-9.
22. Yao Z, McPherson BC, Liu H, et al. Signal transduction of flumazenil-induced preconditioning in myocytes. Am J Physiol Heart Circ Physiol 2001; 280, H1249-55.
23. Vanden Hoek T, Becker LB, Shao ZH, Li CQ, Schumacker PT. Preconditioning in cardiomyocytes protects by attenuating oxidant stress at reperfusion. Circ Res 2000; 86, 541-548.
24. Becker LB, vanden Hoek TL, Shao ZH, Li CQ, Schumacker PT. Generation of superoxide in cardiomyocytes during ischemia before reperfusion. Am J Physiol 1999; 277, H2240-6.
25. Shao ZH, Li CQ, Vanden Hoek TL, et al. Extract from Scutellaria baicalensis Georgi attenuates oxidant stress in cardiomyocytes. J Mol Cell Cardiol 1999; 31, 1885-1895.
26. Yao Z, Tong J, Tan X, et al. Role of reactive oxygen species in acetylcholine-induced preconditioning in cardiomyocytes. Am J Physiol 1999; 277, H2504-9.
27. Page K, Li J, Hodge JA, et al. Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells. J Biol Chem 1999; 274, 22065-22071.
28. Vanden Hoek TL, Becker LB, Shao Z, Li C, Schumacker PT. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J Biol Chem 1998; 273, 18092-18098.
29. Vanden Hoek TL, Li C, Shao Z, Schumacker PT, Becker LB. Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion. J Mol Cell Cardiol 1997; 29, 2571-2583.
30. Vanden Hoek TL, Shao Z, Li C, Schumacker PT, Becker LB. Mitochondrial electron transport can become a significant source of oxidative injury in cardiomyocytes. J Mol Cell Cardiol 1997; 29, 2441-2450.
31. Vanden Hoek TL, Shao Z, Li C, Zak R, Schumacker PT, Becker LB. Reperfusion injury on cardiac myocytes after simulated ischemia. Am J Physiol 1996; 270, H1334-41.